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ARMETL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150171

CDNF Antibody: The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDNF (ARMETL1), Polyclonal Antibody
Full Product Name
CDNF Antibody
Product Gene Name
Product Synonym Names
CDNF; ARMETL1; ARMETL1; Cerebral dopamine neurotrophic factor; ARMET-like protein 1; arginine-rich, mutated in early stage tumors-like 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
CDNF Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody does not cross-react with MANF.
Preparation and Storage
CDNF antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
CDNF peptide (MBS152659) is used for blocking the activity of CDNF antibody (MBS150171)
Molecular Weight
9,806 Da
OMIM
611233
3D Structure
ModBase 3D Structure for Q49AH0
Conjugate
Unconjugated
Immunogen
CDNF antibody was raised against a 9 amino acid synthetic peptide from near the carboxy terminus of human CDNF.
Buffer
CDNF Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ARMETL1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ARMETL1 antibody
CDNF antibody can be used for detection of CDNF by Western blot at 2 - 4 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ARMETL1 antibody

Western blot analysis of CDNF in mouse brain tissue lysate with CDNF antibody at (A) 2 and (B) 4 μg/mL.
Rabbit Anti-ARMETL1 Polyclonal Antibody – Cat# MBS150171

Immunohistochemistry (IHC) of anti-ARMETL1 antibody

Immunohistochemistry of CDNF in human brain tissue with CDNF antibody at 2.5 μg/mL.
Rabbit Anti-ARMETL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150171

Immunofluorescence (IF) of anti-ARMETL1 antibody

Immunofluorescence of CDNF in Human Brain cells with CDNF antibody at 20 μg/mL.
Rabbit Anti-ARMETL1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150171

Immunohistochemistry (IHC) of anti-ARMETL1 antibody

Immunohistochemistry of CDNF in mouse brain tissue with CDNF Antibody at 5 μg/mL.
Rabbit Anti-ARMETL1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150171

Immunofluorescence (IF) of anti-ARMETL1 antibody

Immunofluorescence of CDNF in mouse brain tissue with CDNF Antibody at 20 μg/mL.

Green: CDNF Antibody (4343)
Blue: DAPI staining
Rabbit Anti-ARMETL1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150171

Other Notes

Small volumes of anti-ARMETL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARMETL1 purchase

MBS150171 is an antibody targeting ARMETL1. Also known as CDNF Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARMETL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Cerebral dopamine neurotrophic factor
NCBI Official Synonym Full Names
cerebral dopamine neurotrophic factor
NCBI Official Symbol
CDNF
NCBI Official Synonym Symbols
ARMETL1
UniProt Protein Name
Cerebral dopamine neurotrophic factor
UniProt Synonym Protein Names
ARMET-like protein 1; Conserved dopamine neurotrophic factor
UniProt Gene Name
CDNF
UniProt Synonym Gene Names
ARMETL1
UniProt Entry Name
CDNF_HUMAN
NCBI Protein Information
cerebral dopamine neurotrophic factor; ARMET-like protein 1; conserved dopamine neurotrophic factor; arginine-rich, mutated in early stage tumors-like 1

UniProt Comments for ARMETL1

ARMETL1: Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. Belongs to the ARMET family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: extracellular region

Molecular Function: growth factor activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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