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NLRP13 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150278

NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal… More details

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Product Overview

Online Datasheet in PDF
Product Name
NALP13 (NLRP13), Polyclonal Antibody
Full Product Name
NALP13 Antibody
Product Gene Name
anti-NLRP13 antibody
Product Synonym Names
NALP13; NOD14; PAN13; NALP13; CLR19.7; NOD14; NACHT; LRR and PYD domains-containing protein 13; Nucleotide-binding oligomerization domain protein 14; NLR family, pyrin domain containing 13
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
NALP13 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
NALP13 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
NALP13 peptide (MBS151823) is used for blocking the activity of NALP13 antibody (MBS150278)
Molecular Weight
118,884 Da
OMIM
609660
3D Structure
ModBase 3D Structure for Q86W25
Conjugate
Unconjugated
Immunogen
NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13.
Buffer
NALP13 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-NLRP13 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-NLRP13 antibody
NALP13 antibody can be used for detection of NALP13 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-NLRP13 antibody

Western blot analysis of NALP13 in K562 cell lysate with NALP13 antibody at 1 μg/mL.
Rabbit Anti-NLRP13 Polyclonal Antibody – Cat# MBS150278

Immunocytochemistry (IHC) of anti-NLRP13 antibody

Immunocytochemistry of NALP13 in K562 cells with NALP13 antibody at 2.5 μg/mL.
Rabbit Anti-NLRP13 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150278

Immunofluorescence (IF) of anti-NLRP13 antibody

Immunofluorescence of NALP13 in K562 cells with NALP13 antibody at 20 μg/mL.
Rabbit Anti-NLRP13 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150278

Other Notes

Small volumes of anti-NLRP13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NLRP13 purchase

MBS150278 is an antibody targeting NLRP13. Also known as NALP13 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NLRP13. It may not necessarily be applicable to this product.

NCBI GI #
119592826
NCBI GeneID
126204
NCBI Accession #
EAW72420
UniProt Primary Accession #
Q86W25
UniProt Secondary Accession #
Q7RTR5
UniProt Related Accession #
Q86W25
NCBI Official Full Name
NACHT, leucine rich repeat and PYD containing 13, isoform CRA_b, partial
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 13
NCBI Official Symbol
NLRP13
NCBI Official Synonym Symbols
NOD14; PAN13; NALP13; CLR19.7
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 13
UniProt Synonym Protein Names
Nucleotide-binding oligomerization domain protein 14
Protein Family
NACHT, LRR and PYD domains-containing protein
UniProt Gene Name
NLRP13
UniProt Synonym Gene Names
NALP13; NOD14
UniProt Entry Name
NAL13_HUMAN
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 13; NACHT, LRR and PYD containing protein 13; NACHT, leucine rich repeat and PYD containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13

NCBI Summary for NLRP13

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
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UniProt Comments for NLRP13

NLRP13: Involved in inflammation (Potential). Belongs to the NLRP family.

Chromosomal Location of Human Ortholog: 19q13.43

Molecular Function: ATP binding

Research Articles on NLRP13

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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