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TSLP Receptor (CRLF2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150294

TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TSLP Receptor (Crlf2), Polyclonal Antibody
Full Product Name
TSLP Receptor Antibody
Product Gene Name
Product Synonym Names
TSLP Receptor; CRLM2; Ly114; Tpte2; Tslpr; Crlm2; Cytokine receptor-like factor 2; Cytokine receptor-like molecule 2; CRLM-2; cytokine receptor-like factor 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
TSLP Receptor Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
TSLP Receptor antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Molecular Weight
13,236 Da
3D Structure
ModBase 3D Structure for Q8CII9
Conjugate
Unconjugated
Immunogen
TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor.
Buffer
TSLP Receptor Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-Crlf2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-Crlf2 antibody
TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 mug/mL. Despite its predicted molecular weight, TSLP-R often migrates at a higher molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-Crlf2 antibody

Western blot analysis of TSLP Receptor in human liver tissue lysate with TSLP Receptor antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Rabbit Anti-CRLF2 Polyclonal Antibody – Cat# MBS150294

Immunohistochemistry (IHC) of anti-Crlf2 antibody

Immunohistochemistry of TSLP-R in human liver tissue with TSLP-R antibody at 5 μg/mL.
Rabbit Anti-CRLF2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150294

Immunofluorescence (IF) of anti-Crlf2 antibody

Immunofluorescence of TSLP Receptor in Human Liver tissue with TSLP Receptor antibody at 20 μg/mL.
Rabbit Anti-CRLF2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150294

Other Notes

Small volumes of anti-Crlf2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Crlf2 purchase

MBS150294 is an antibody targeting Crlf2. Also known as TSLP Receptor Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Crlf2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytokine receptor-like factor 2
NCBI Official Synonym Full Names
cytokine receptor-like factor 2
NCBI Official Symbol
Crlf2
NCBI Official Synonym Symbols
CRLM2; Ly114; Tpte2; Tslpr
UniProt Protein Name
Cytokine receptor-like factor 2
UniProt Synonym Protein Names
Cytokine receptor-like molecule 2; CRLM-2; Thymic stromal lymphopoietin protein receptor; TSLP receptor; Type I cytokine receptor delta 1
UniProt Gene Name
Crlf2
UniProt Synonym Gene Names
Crlm2; Tpte2; Tslpr; CRLM-2; TSLP receptor
UniProt Entry Name
CRLF2_MOUSE
NCBI Protein Information
cytokine receptor-like factor 2; CRLM-2; delta 1; TSLP receptor; lymphocyte antigen 114; type I cytokine receptor delta 1; cytokine receptor-like molecule 2; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

UniProt Comments for Crlf2

CRLF2: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. Belongs to the type I cytokine receptor family. Type 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: membrane; cell; plasma membrane; integral to membrane; extracellular region

Molecular Function: cytokine activity

Biological Process: immunoglobulin secretion during immune response; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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