Rabbit Anti-DISP2 Polyclonal Antibody – Cat# MBS150321

Western blot analysis of Disp2 in rat brain tissue lysate with Disp2 antibody at (A) 1 and (B) 2 μg/mL.

DISP2 Antibody – Rabbit Polyclonal

Name: DISP2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS150321
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150321

Disp2 Antibody: Disp2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Disp2, Polyclonal Antibody

Full Product Name

Disp2 Antibody

Product Gene Name

anti-DISP2 antibody

Product Synonym Names

Disp2; DISPB; HsT16908; DISPB; KIAA1742; Protein dispatched homolog 2; dispatched homolog 2 (Drosophila)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid

Purity/Purification

Disp2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL (lot specific)

Preparation and Storage

Disp2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antibody/Peptide Pairs

Disp2 peptide (MBS151984) is used for blocking the activity of Disp2 antibody (MBS150321)

Molecular Weight

152,003 Da

OMIM

607503

3D Structure

ModBase 3D Structure for A7MBM2

Conjugate

Unconjugated

Immunogen

Disp2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human Disp2.

Buffer

Disp2 Antibody is supplied in PBS containing 0.02% sodium azide.

Applications Tested/Suitable for anti-DISP2 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-DISP2 antibody

Disp2 antibody can be used for the detection of Disp2 by Western blot at 1 - 2 mug/mL.

Other Notes

Small volumes of anti-DISP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DISP2 purchase

MBS150321 is an antibody targeting DISP2. Also known as Disp2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DISP2. It may not necessarily be applicable to this product.

NCBI GI #

160380692

NCBI GeneID

85455

NCBI Accession #

A7MBM2.2

UniProt Primary Accession #

A7MBM2

UniProt Secondary Accession #

Q6AHW3; Q9C0C1

UniProt Related Accession #

A7MBM2

NCBI Official Full Name

Protein dispatched homolog 2

NCBI Official Synonym Full Names

dispatched homolog 2 (Drosophila)

NCBI Official Symbol

DISP2

NCBI Official Synonym Symbols

DISPB; HsT16908

UniProt Protein Name

Protein dispatched homolog 2

Protein Family

Protein dispatched

UniProt Gene Name

DISP2

UniProt Synonym Gene Names

DISPB; KIAA1742

UniProt Entry Name

DISP2_HUMAN

NCBI Protein Information

protein dispatched homolog 2; dispatched B

NCBI Summary for DISP2

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008]

UniProt Comments for DISP2

DISP2: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: plasma membrane; integral to membrane

Biological Process: smoothened signaling pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DISP2 antibody

Reference Product	PubMed Publications
STK36 antibody	>1 publications with DISP2 and STK36
KIF7 antibody	>1 publications with DISP2 and KIF7
KIF27 antibody	>1 publications with DISP2 and KIF27

Pathways associated with anti-DISP2 antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Hedgehog Ligand Biogenesis Pathway antibodies	Hedgehog Ligand Biogenesis Pathway Diagram
Processing-defective Hh Variants Abrogate Ligand Secretion Pathway antibodies	Processing-defective Hh Variants Abrogate Ligand Secretion Pathway Diagram
Release Of Hh-Np From The Secreting Cell Pathway antibodies	Release Of Hh-Np From The Secreting Cell Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Hedgehog Pathway antibodies	Signaling By Hedgehog Pathway Diagram

Organs/Tissues associated with anti-DISP2 antibody

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>2 publications with DISP2 and Pancreas
Embryonic Tissue Antibodies	>1 publications with DISP2 and Embryonic Tissue
Uncharacterized Tissue Antibodies	>1 publications with DISP2 and Uncharacterized Tissue
Lung Antibodies	>1 publications with DISP2 and Lung
Testis Antibodies	>1 publications with DISP2 and Testis
Brain Antibodies	>1 publications with DISP2 and Brain