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PCBP4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150341

MCG10 Antibody: MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MCG10 (PCBP4), Polyclonal Antibody
Full Product Name
MCG10 Antibody
Product Gene Name
anti-PCBP4 antibody
Product Synonym Names
MCG10; CBP; LIP4; MCG10Alpha-CP4; poly(rC) binding protein 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
MCG10 Antibody is affinity chromatography purified via peptide column.
Preparation and Storage
MCG10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
MCG10 peptide (MBS153196) is used for blocking the activity of MCG10 antibody (MBS150341)
Molecular Weight
37,078 Da
OMIM
608503
3D Structure
ModBase 3D Structure for P57723
Conjugate
Unconjugated
Immunogen
MCG10 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human MCG10.
Buffer
MCG10 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-PCBP4 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-PCBP4 antibody
MCG10 antibody can be used for detection of MCG10 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 1 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-PCBP4 antibody

Western blot analysis of MCG10 in HeLa cell lysate with MCG10 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Rabbit Anti-PCBP4 Polyclonal Antibody – Cat# MBS150341

Immunocytochemistry (IHC) of anti-PCBP4 antibody

Immunocytochemistry of MCG10 in HeLa cells with MCG10 antibody at 1 μg/mL.
Rabbit Anti-PCBP4 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150341

Immunofluorescence (IF) of anti-PCBP4 antibody

Immunofluorescence of MCG10 in Hela cells with MCG10 antibody at 20 μg/mL.
Rabbit Anti-PCBP4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150341

Other Notes

Small volumes of anti-PCBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCBP4 purchase

MBS150341 is an antibody targeting PCBP4. Also known as MCG10 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PCBP4. It may not necessarily be applicable to this product.

NCBI GI #
119585570
NCBI GeneID
57060
NCBI Accession #
EAW65166
UniProt Primary Accession #
P57723
UniProt Secondary Accession #
Q96AH7
UniProt Related Accession #
P57723
NCBI Official Full Name
poly(rC) binding protein 4, isoform CRA_b
NCBI Official Synonym Full Names
poly(rC) binding protein 4
NCBI Official Symbol
PCBP4
NCBI Official Synonym Symbols
CBP; LIP4; MCG10
UniProt Protein Name
Poly(rC)-binding protein 4
UniProt Synonym Protein Names
Alpha-CP4
Protein Family
Poly(rC)-binding protein
UniProt Gene Name
PCBP4
UniProt Entry Name
PCBP4_HUMAN
NCBI Protein Information
poly(rC)-binding protein 4; poly(rC)-binding protein 4; alpha-CP4; LYST-interacting protein; RNA binding protein MCG10

NCBI Summary for PCBP4

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for PCBP4

PCBP4: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: cytoplasm; ribonucleoprotein complex

Molecular Function: DNA binding; RNA binding
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Research Articles on PCBP4

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PCBP4 antibody

 Reference Product  PubMed Publications
 PCBP1 antibody  >1 publications with PCBP4 and PCBP1

Pathways associated with anti-PCBP4 antibody

 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram

Diseases associated with anti-PCBP4 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with PCBP4 and Liver Diseases

Organs/Tissues associated with anti-PCBP4 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with PCBP4 and Lung
 Liver Antibodies  >1 publications with PCBP4 and Liver
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