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TTC5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150525

TTC5 Antibody: Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that… More details

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Product Overview

Online Datasheet in PDF
Product Name
TTC5, Polyclonal Antibody
Full Product Name
TTC5 Antibody
Product Gene Name
Product Synonym Names
TTC5; Strap; Tetratricopeptide repeat protein 5; Stress-responsive activator of p300; TPR repeat protein 5; tetratricopeptide repeat domain 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
TTC5 Antibody is immunoaffinity purified IgG.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
TTC5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
TTC5 peptide (MBS152254) is used for blocking the activity of TTC5 antibody (MBS150525)
Molecular Weight
48,928 Da
3D Structure
ModBase 3D Structure for Q8N0Z6
Conjugate
Unconjugated
Immunogen
TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5.
Buffer
TTC5 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TTC5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TTC5 antibody
TTC5 antibody can be used for the detection of TTC5 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-TTC5 antibody

Western blot analysis of TTC5 in RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Rabbit Anti-TTC5 Polyclonal Antibody – Cat# MBS150525

Immunohistochemistry (IHC) of anti-TTC5 antibody

Immunohistochemistry of TTC5 in mouse brain tissue with TTC5 antibody at 10 μg/mL.
Rabbit Anti-TTC5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150525

Immunofluorescence (IF) of anti-TTC5 antibody

Immunofluorescence of TTC5 in Mouse Brain cells with TTC5 antibody at 20 μg/mL.
Rabbit Anti-TTC5 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150525

Other Notes

Small volumes of anti-TTC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TTC5 purchase

MBS150525 is an antibody targeting TTC5. Also known as TTC5 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TTC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Tetratricopeptide repeat protein 5
UniProt Protein Name
Tetratricopeptide repeat protein 5
UniProt Synonym Protein Names
Stress-responsive activator of p300; Strap
UniProt Gene Name
TTC5
UniProt Synonym Gene Names
TPR repeat protein 5; Strap
UniProt Entry Name
TTC5_HUMAN

UniProt Comments for TTC5

TTC5: Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: DNA binding; chromatin binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; DNA repair
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TTC5 antibody

 Reference Product  PubMed Publications
 TP53 antibody  >1 publications with TTC5 and TP53

Diseases associated with anti-TTC5 antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >2 publications with TTC5 and Death
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