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TOMM70A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150544

TOM70 Antibody: The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TOM70 (TOMM70A), Polyclonal Antibody
Full Product Name
TOM70 Antibody
Product Gene Name
anti-TOMM70A antibody
Product Synonym Names
TOM70; KIAA0719; TOM70; Mitochondrial import receptor subunit TOM70; Mitochondrial precursor proteins import receptor; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
TOM70 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
TOM70 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
TOM70 peptide (MBS152688) is used for blocking the activity of TOM70 antibody (MBS150544)
Molecular Weight
67,455 Da
OMIM
606081
3D Structure
ModBase 3D Structure for O94826
Conjugate
Unconjugated
Immunogen
TOM70 antibody was raised against a 15 amino acid synthetic peptide near the center of human TOM70.
Buffer
TOM70 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TOMM70A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TOMM70A antibody
TOM70 antibody can be used for detection of TOM70 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-TOMM70A antibody

Western blot analysis of TOM70 in rat brain tissue lysate with TOM70 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-TOMM70A Polyclonal Antibody – Cat# MBS150544

Immunohistochemistry (IHC) of anti-TOMM70A antibody

Immunohistochemistry of TOM70 in mouse brain tissue with TOM70 antibody at 2.5 μg/mL.
Rabbit Anti-TOMM70A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150544

Immunofluorescence (IF) of anti-TOMM70A antibody

Immunofluorescence of TOM70 in Mouse Brain cells with TOM70 antibody at 20 μg/mL.
Rabbit Anti-TOMM70A Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150544

Other Notes

Small volumes of anti-TOMM70A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOMM70A purchase

MBS150544 is an antibody targeting TOMM70A. Also known as TOM70 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TOMM70A. It may not necessarily be applicable to this product.

NCBI GI #
54607135
NCBI GeneID
9868
NCBI Accession #
NP_055635
UniProt Primary Accession #
O94826
UniProt Secondary Accession #
D3DN48
UniProt Related Accession #
O94826
GenBank Nucleotide #
NM_014820.4
NCBI Official Full Name
mitochondrial import receptor subunit TOM70
NCBI Official Synonym Full Names
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
NCBI Official Symbol
TOMM70A
UniProt Protein Name
Mitochondrial import receptor subunit TOM70
UniProt Synonym Protein Names
Mitochondrial precursor proteins import receptor; Translocase of outer membrane 70 kDa subunit
Protein Family
Mitochondrial import receptor
UniProt Gene Name
TOMM70A
UniProt Synonym Gene Names
KIAA0719; TOM70
UniProt Entry Name
TOM70_HUMAN
NCBI Protein Information
mitochondrial import receptor subunit TOM70; translocase of outer membrane 70 kDa subunit; mitochondrial precursor proteins import receptor

NCBI Summary for TOMM70A

This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. [provided by RefSeq, Oct 2011]

UniProt Comments for TOMM70A

TOMM70A: Receptor that accelerates the import of all mitochondrial precursor proteins. Belongs to the Tom70 family.

Protein type: Receptor, protein translocating; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q12.2

Cellular Component: mitochondrial outer membrane translocase complex; mitochondrion; membrane; integral to membrane

Molecular Function: protein binding; protein transmembrane transporter activity

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion
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Research Articles on TOMM70A

1. Blockade of mitochondrial protein import triggers the recruitment of PARK2, by PINK1, to the TOMM machinery.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TOMM70A antibody

 Reference Product  PubMed Publications
 TIMM9 antibody  >1 publications with TOMM70A and TIMM9
 TOMM40 antibody  >1 publications with TOMM70A and TOMM40
 TOMM20 antibody  >1 publications with TOMM70A and TOMM20
 TOMM22 antibody  >1 publications with TOMM70A and TOMM22

Pathways associated with anti-TOMM70A antibody

 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mitochondrial Protein Import Pathway antibodies  Mitochondrial Protein Import Pathway Diagram

Diseases associated with anti-TOMM70A antibody

 Disease Name  Pubmed Publications
 Movement Disorders Antibodies  >1 publications with TOMM70A and Movement Disorders
 Liver Diseases Antibodies  >1 publications with TOMM70A and Liver Diseases
 Necrosis Antibodies  >1 publications with TOMM70A and Necrosis

Organs/Tissues associated with anti-TOMM70A antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with TOMM70A and Liver
 Brain Antibodies  >2 publications with TOMM70A and Brain
 Prostate Antibodies  >1 publications with TOMM70A and Prostate
 Thyroid Antibodies  >1 publications with TOMM70A and Thyroid
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