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SEC16B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150562

LZTR2 Antibody: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is… More details

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Product Overview

Online Datasheet in PDF
Product Name
LZTR2 (SEC16B), Polyclonal Antibody
Full Product Name
LZTR2 Antibody
Product Gene Name
Product Synonym Names
LZTR2; RGPR; LZTR2; SEC16S; PGPR-p117; KIAA1928; RGPR; Protein transport protein Sec16B; Leucine zipper transcription regulator 2; RGPR-p117; SEC16 homolog B (S. cerevisiae)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
LZTR2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
LZTR2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
LZTR2 peptide (MBS153266) is used for blocking the activity of LZTR2 antibody (MBS150562)
Molecular Weight
59,124 Da
OMIM
612855
3D Structure
ModBase 3D Structure for Q96JE7
Conjugate
Unconjugated
Immunogen
LZTR2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LZTR2.
Buffer
LZTR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SEC16B antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SEC16B antibody
LZTR2 antibody can be used for detection of LZTR2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SEC16B antibody

Western blot analysis of LZTR2 in mouse kidney tissue lysate with LZTR2 antibody at 1 μg/mL.
Rabbit Anti-SEC16B Polyclonal Antibody – Cat# MBS150562

Immunohistochemistry (IHC) of anti-SEC16B antibody

Immunohistochemistry of LZTR2 in mouse kidney tissue with LZTR2 antibody at 5 μg/mL.
Rabbit Anti-SEC16B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150562

Immunofluorescence (IF) of anti-SEC16B antibody

Immunofluorescence of LZTR2 in mouse kidney tissue with LZTR2 antibody at 20 μg/mL.
Rabbit Anti-SEC16B Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150562

Other Notes

Small volumes of anti-SEC16B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEC16B purchase

MBS150562 is an antibody targeting SEC16B. Also known as LZTR2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEC16B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein transport protein Sec16B
NCBI Official Synonym Full Names
SEC16 homolog B (S. cerevisiae)
NCBI Official Symbol
SEC16B
NCBI Official Synonym Symbols
RGPR; LZTR2; SEC16S; PGPR-p117
UniProt Protein Name
Protein transport protein Sec16B
UniProt Synonym Protein Names
Leucine zipper transcription regulator 2; Regucalcin gene promoter region-related protein p117; RGPR-p117; SEC16 homolog B
UniProt Gene Name
SEC16B
UniProt Synonym Gene Names
KIAA1928; LZTR2; RGPR; SEC16S; RGPR-p117
UniProt Entry Name
SC16B_HUMAN
NCBI Protein Information
protein transport protein Sec16B; RGPR-p117; protein SEC16 homolog B; leucine zipper transcription regulator 2; regucalcin gene promotor region related protein; regucalcin gene promoter region-related protein p117

NCBI Summary for SEC16B

SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009]

UniProt Comments for SEC16B

SEC16B: Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization. Belongs to the SEC16 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle

Biological Process: peroxisome fission; endoplasmic reticulum organization and biogenesis; COPII coating of Golgi vesicle; protein transport; peroxisome organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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