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EFCAB4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150604

EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EFCAB4A, Polyclonal Antibody
Full Product Name
EFCAB4A Antibody
Product Gene Name
Product Synonym Names
EFCAB4A; CRACR2B; CRACR2B; EF-hand calcium-binding domain-containing protein 4A; Calcium release-activated calcium channel regulator 2B; CRAC channel regulator 2B; EF-hand calcium binding domain 4A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
EFCAB4A Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
EFCAB4A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
EFCAB4A peptide (MBS152429) is used for blocking the activity of EFCAB4A antibody (MBS150604)
Molecular Weight
32,746 Da
OMIM
614177
3D Structure
ModBase 3D Structure for Q8N4Y2
Conjugate
Unconjugated
Immunogen
EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A.
Buffer
EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-EFCAB4A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-EFCAB4A antibody
EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-EFCAB4A antibody

Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-EFCAB4A Polyclonal Antibody – Cat# MBS150604

Other Notes

Small volumes of anti-EFCAB4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EFCAB4A purchase

MBS150604 is an antibody targeting EFCAB4A. Also known as EFCAB4A Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EFCAB4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
EF-hand calcium-binding domain-containing protein 4A isoform 2
NCBI Official Synonym Full Names
calcium release activated channel regulator 2B
NCBI Official Symbol
CRACR2B
NCBI Official Synonym Symbols
EFCAB4A
UniProt Protein Name
EF-hand calcium-binding domain-containing protein 4A
UniProt Synonym Protein Names
Calcium release-activated calcium channel regulator 2B; CRAC channel regulator 2B; Calcium release-activated channel regulator 2B
UniProt Gene Name
CRACR2B
UniProt Synonym Gene Names
EFCAB4A; CRAC channel regulator 2B
UniProt Entry Name
EFC4A_HUMAN
NCBI Protein Information
EF-hand calcium-binding domain-containing protein 4A; CRAC regulator 2B; CRAC channel regulator 2B; EF-hand calcium binding domain 4A; calcium release-activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B

UniProt Comments for EFCAB4A

EFCAB4A: Plays a role in store-operated Ca(2+) entry (SOCE). Belongs to the EFCAB4 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm

Molecular Function: calcium ion binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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