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LRRTM2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150605

LRRTM2 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LRRTM2, Polyclonal Antibody
Full Product Name
LRRTM2 Antibody
Product Gene Name
Product Synonym Names
LRRTM2; KIAA0416; LRRN2; Leucine-rich repeat transmembrane neuronal protein 2; Leucine-rich repeat neuronal 2 protein; leucine rich repeat transmembrane neuronal 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
LRRTM2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
LRRTM2 antibody is predicted to not cross-react with other LRRTM family members.
Preparation and Storage
LRRTM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
LRRTM2 peptide (MBS152192) is used for blocking the activity of LRRTM2 antibody (MBS150605)
Molecular Weight
59,076 Da
OMIM
610868
3D Structure
ModBase 3D Structure for O43300
Conjugate
Unconjugated
Immunogen
LRRTM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM2.
Buffer
LRRTM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-LRRTM2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-LRRTM2 antibody
LRRTM2 antibody can be used for detection of LRRTM2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-LRRTM2 antibody

Western blot analysis of LRRTM2 in SK-N-SH cell lysate with LRRTM2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-LRRTM2 Polyclonal Antibody – Cat# MBS150605

Immunohistochemistry (IHC) of anti-LRRTM2 antibody

Immunohistochemistry of LRRTM2 in human brain tissue with LRRTM2 antibody at 2.5 μg/mL.
Rabbit Anti-LRRTM2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150605

Immunofluorescence (IF) of anti-LRRTM2 antibody

Immunofluorescence of LRRTM2 in human brain tissue with LRRTM2 antibody at 20 μg/mL.
Rabbit Anti-LRRTM2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150605

Other Notes

Small volumes of anti-LRRTM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRRTM2 purchase

MBS150605 is an antibody targeting LRRTM2. Also known as LRRTM2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRTM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
leucine-rich repeat transmembrane neuronal protein 2
NCBI Official Synonym Full Names
leucine rich repeat transmembrane neuronal 2
NCBI Official Symbol
LRRTM2
UniProt Protein Name
Leucine-rich repeat transmembrane neuronal protein 2
UniProt Synonym Protein Names
Leucine-rich repeat neuronal 2 protein
UniProt Gene Name
LRRTM2
UniProt Synonym Gene Names
KIAA0416; LRRN2
UniProt Entry Name
LRRT2_HUMAN
NCBI Protein Information
leucine-rich repeat transmembrane neuronal protein 2; leucine-rich repeat neuronal 2 protein; leucine-rich repeat transmembrane neuronal 2 protein

UniProt Comments for LRRTM2

LRRTM2: Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B. Belongs to the LRRTM family.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q31.2

Cellular Component: postsynaptic membrane; integral to membrane; excitatory synapse; cell junction

Molecular Function: neurexin binding

Biological Process: synapse organization and biogenesis; negative regulation of receptor internalization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LRRTM2 antibody

Organs/Tissues associated with anti-LRRTM2 antibody

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