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Coronin 7 (CORO7) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150621

Coronin 7 Antibody: Coronins, such as Coronin 7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins whose function is thought to be regulating the cytoskeleton. Unlike other cytoplasmically localized Coronins, Coronin 7… More details

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Product Overview

Online Datasheet in PDF
Product Name
Coronin 7 (CORO7), Polyclonal Antibody
Full Product Name
Coronin 7 Antibody
Product Gene Name
Product Synonym Names
Coronin 7; CRN7; POD1; 0610011B16Rik; Coronin-7; 70 kDa WD repeat tumor rejection antigen homolog; Crn7; coronin7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Coronin 7 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Multiple isoforms of Coronin 7 are known to exist
Preparation and Storage
Coronin 7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Molecular Weight
98,579 Da
OMIM
611668
3D Structure
ModBase 3D Structure for P57737
Conjugate
Unconjugated
Immunogen
Coronin 7 antibody was raised against an 17 amino acid synthetic peptide near the carboxy terminus of human Coronin 7.
Buffer
Coronin 7 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-CORO7 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CORO7 antibody
Coronin 7 antibody can be used for detection of Coronin 7 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-CORO7 antibody

Western blot analysis of Coronin 7 in rat lung tissue lysate with Coronin 7 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-CORO7 Polyclonal Antibody – Cat# MBS150621

Immunohistochemistry (IHC) of anti-CORO7 antibody

Immunohistochemistry of Coronin 7 in rat lung tissue with Coronin 7 antibody at 2.5 μg/mL.
Rabbit Anti-CORO7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150621

Immunofluorescence (IF) of anti-CORO7 antibody

Immunofluorescence of Coronin 7 in rat lung tissue with Coronin 7 antibody at 20 μg/mL.
Rabbit Anti-CORO7 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150621

Other Notes

Small volumes of anti-CORO7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CORO7 purchase

MBS150621 is an antibody targeting CORO7. Also known as Coronin 7 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CORO7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
coronin-7 isoform 1
NCBI Official Synonym Full Names
coronin 7
NCBI Official Symbol
CORO7
NCBI Official Synonym Symbols
CRN7; POD1; 0610011B16Rik
UniProt Protein Name
Coronin-7
UniProt Synonym Protein Names
70 kDa WD repeat tumor rejection antigen homolog
Protein Family
UniProt Gene Name
CORO7
UniProt Synonym Gene Names
Crn7
UniProt Entry Name
CORO7_HUMAN
NCBI Protein Information
coronin-7; 70 kDa WD repeat tumor rejection antigen homolog

NCBI Summary for CORO7

Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]).[supplied by OMIM, Mar 2008]

UniProt Comments for CORO7

coronin 7: May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi. Belongs to the WD repeat coronin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: Golgi membrane; Golgi apparatus; membrane; cytoplasmic membrane-bound vesicle; integral to membrane; trans-Golgi network; cytosol; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; actin binding

Biological Process: protein transport; actin filament polymerization; Golgi to endosome transport; actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CORO7 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CORO7 and Brain
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