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T-Cadherin (ENTPD3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150632

T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin… More details

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Product Overview

Online Datasheet in PDF
Product Name
T-cadherin (ENTPD3), Polyclonal Antibody
Full Product Name
T-cadherin Antibody
Product Gene Name
anti-ENTPD3 antibody
Product Synonym Names
T-cadherin; HB6; CD39L3; NTPDase-3; Ectonucleoside triphosphate diphosphohydrolase 3; CD39 antigen-like 3; NTPDase 3; ectonucleoside triphosphate diphosphohydrolase 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
T-cadherin Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of T-cadherin are known to exist.
Preparation and Storage
T-cadherin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
T-cadherin peptide (MBS152790) is used for blocking the activity of T-cadherin antibody (MBS150632)
Molecular Weight
Predicted: 78; 84 kDa

Observed: 85 kDa
OMIM
603161
3D Structure
ModBase 3D Structure for O75355
Conjugate
Unconjugated
Immunogen
T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin.
Buffer
T-cadherin Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ENTPD3 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ENTPD3 antibody
T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ENTPD3 antibody

Western blot analysis of T-cadherin in 3T3 lysate with T-cadherin antibody at (A) 0.5 and (B) 1 μg/mL.
Rabbit Anti-ENTPD3 Polyclonal Antibody – Cat# MBS150632

Immunofluorescence (IF) of anti-ENTPD3 antibody

Immunofluorescence of T-cadherin in K562 cells with T-cadherin antibody at 20 μg/mL.
Rabbit Anti-ENTPD3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150632

Immunofluorescence (IF) of anti-ENTPD3 antibody

Immunofluorescence of T-cadherin in 3T3 cells with T-cadherin antibody at 2 μg/mL.
Rabbit Anti-ENTPD3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150632

Immunohistochemistry (IHC) of anti-ENTPD3 antibody

Immunohistochemistry of T cadherin in mouse brain tissue with T cadherin Antibody at 5 μg/mL.
Rabbit Anti-ENTPD3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150632

Immunofluorescence (IF) of anti-ENTPD3 antibody

Immunofluorescence of T cadherin in mouse brain tissue with T cadherin Antibody at 20 μg/mL.

Green: T-cadherin antibody (3583)
Red: Phylloidin staining
Blue: DAPI staining
Rabbit Anti-ENTPD3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150632

Other Notes

Small volumes of anti-ENTPD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENTPD3 purchase

MBS150632 is an antibody targeting ENTPD3. Also known as T-cadherin Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD3. It may not necessarily be applicable to this product.

NCBI GI #
166197701
NCBI GeneID
956
NCBI Accession #
NP_001248
UniProt Primary Accession #
O75355
UniProt Secondary Accession #
O60495; Q8N6K2; B2R8D0; G5E9N0
UniProt Related Accession #
O75355
GenBank Nucleotide #
NM_001248.2
NCBI Official Full Name
Homo sapiens ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), mRNA
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 3
NCBI Official Symbol
ENTPD3
NCBI Official Synonym Symbols
HB6; CD39L3; NTPDase-3
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 3
UniProt Synonym Protein Names
CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6
Protein Family
Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name
ENTPD3
UniProt Synonym Gene Names
CD39L3; NTPDase 3; Ecto-ATPDase 3; Ecto-ATPase 3
UniProt Entry Name
ENTP3_HUMAN
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 3; NTPDase 3; ecto-ATPase 3; ecto-ATPDase 3; ecto-apyrase 3; CD39 antigen-like 3; ecto-ATP diphosphohydrolase 3

NCBI Summary for ENTPD3

This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]

UniProt Comments for ENTPD3

ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein); Membrane protein, multi-pass; EC 3.6.1.5; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: nucleoside diphosphate catabolic process; nucleoside triphosphate catabolic process
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Research Articles on ENTPD3

1. NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ENTPD3 antibody

 Reference Product  PubMed Publications
 ENTPD2 antibody  >2 publications with ENTPD3 and ENTPD2
 ENTPD6 antibody  >1 publications with ENTPD3 and ENTPD6
 NT5E antibody  >1 publications with ENTPD3 and NT5E
 ENTPD5 antibody  >1 publications with ENTPD3 and ENTPD5

Pathways associated with anti-ENTPD3 antibody

 Products by Pathway  Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram

Diseases associated with anti-ENTPD3 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with ENTPD3 and Inflammation

Organs/Tissues associated with anti-ENTPD3 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with ENTPD3 and Nerve
 Liver Antibodies  >1 publications with ENTPD3 and Liver
 Kidney Antibodies  >1 publications with ENTPD3 and Kidney
 Pancreas Antibodies  >1 publications with ENTPD3 and Pancreas
 Brain Antibodies  >1 publications with ENTPD3 and Brain
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