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LEMD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150661

LEMD2 Antibody: The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by a group of lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm. One such protein, LEMD2 (LEM domain-containing protein 2), is a… More details

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Product Overview

Online Datasheet in PDF
Product Name
LEMD2, Polyclonal Antibody
Full Product Name
LEMD2 Antibody
Product Gene Name
Product Synonym Names
LEMD2; NET25; dJ482C21.1; LEM domain-containing protein 2; hLEM2; LEM domain containing 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
LEMD2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of LEMD2 are known to exist; this antibody will detect only the longer isoform.
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
LEMD2 peptide (MBS152760) is used for blocking the activity of LEMD2 antibody (MBS150661)
Molecular Weight
23,520 Da
3D Structure
ModBase 3D Structure for Q8NC56
Conjugate
Unconjugated
Immunogen
LEMD2 antibody was raised against a 16 amino acid synthetic peptide near the center of human LEMD2.
Buffer
LEMD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-LEMD2 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-LEMD2 antibody
LEMD2 antibody can be used for detection of LEMD2 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 2.5 mug/mL.

Western Blot (WB) of anti-LEMD2 antibody

Western blot analysis of LEMD2 in 293 cell lysate with LEMD2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-LEMD2 Polyclonal Antibody – Cat# MBS150661

Immunocytochemistry (IHC) of anti-LEMD2 antibody

Immunocytochemistry of LEMD2 in 3T3 cells with LEMD2 antibody at 2.5 μg/mL.
Rabbit Anti-LEMD2 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150661

Immunofluorescence (IF) of anti-LEMD2 antibody

Immunofluorescence of LEMD2 in 3T3 cells with LEMD2 antibody at 20 μg/mL.
Rabbit Anti-LEMD2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150661

Other Notes

Small volumes of anti-LEMD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LEMD2 purchase

MBS150661 is an antibody targeting LEMD2. Also known as LEMD2 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LEMD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
LEM domain-containing protein 2 isoform 1
NCBI Official Synonym Full Names
LEM domain containing 2
NCBI Official Symbol
LEMD2
NCBI Official Synonym Symbols
NET25; dJ482C21.1
UniProt Protein Name
LEM domain-containing protein 2
UniProt Gene Name
LEMD2
UniProt Synonym Gene Names
hLEM2
UniProt Entry Name
LEMD2_HUMAN
NCBI Protein Information
LEM domain-containing protein 2; hLEM2

UniProt Comments for LEMD2

LEMD2: Involved in nuclear structure organization.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Nuclear envelope

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: nuclear membrane; membrane; integral to nuclear inner membrane

Biological Process: negative regulation of MAPKKK cascade
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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