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FAIM2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150668

FAIM2 Antibody: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer.… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FAIM2, Polyclonal Antibody
Full Product Name
FAIM2 Antibody
Product Gene Name
anti-FAIM2 antibody
Product Synonym Names
FAIM2; LFG; LFG2; NGP35; NMP35; TMBIM2; KIAA0950; LFG; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Fas apoptotic inhibitory molecule 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
FAIM2 Antibody is affinity chromatography purified via peptide column.
Preparation and Storage
FAIM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
FAIM2 peptide (MBS152571) is used for blocking the activity of FAIM2 antibody (MBS150668)
Molecular Weight
30,448 Da
OMIM
604306
3D Structure
ModBase 3D Structure for Q9BWQ8
Conjugate
Unconjugated
Immunogen
FAIM2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human FAIM2.
Buffer
FAIM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-FAIM2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FAIM2 antibody
FAIM2 antibody can be used for detection of FAIM2 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.

Western Blot (WB) of anti-FAIM2 antibody

Western blot analysis of FAIM2 in EL4 cell lysate with FAIM2 antibody at (A) 0.5 and (B) 1 μg/mL.
Rabbit Anti-FAIM2 Polyclonal Antibody – Cat# MBS150668

Immunohistochemistry (IHC) of anti-FAIM2 antibody

Immunohistochemistry of FAIM2 in mouse brain tissue with FAIM2 antibody at 5 μg/mL.
Rabbit Anti-FAIM2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150668

Other Notes

Small volumes of anti-FAIM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAIM2 purchase

MBS150668 is an antibody targeting FAIM2. Also known as FAIM2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FAIM2. It may not necessarily be applicable to this product.

NCBI GI #
6273281
NCBI GeneID
23017
NCBI Accession #
AAF06327
UniProt Primary Accession #
Q9BWQ8
UniProt Secondary Accession #
Q9UJY9; Q9Y2F7; A8K1W6; B3KR08
UniProt Related Accession #
Q9BWQ8
NCBI Official Full Name
lifeguard
NCBI Official Synonym Full Names
Fas apoptotic inhibitory molecule 2
NCBI Official Symbol
FAIM2
NCBI Official Synonym Symbols
LFG; LFG2; NGP35; NMP35; TMBIM2
UniProt Protein Name
Protein lifeguard 2
UniProt Synonym Protein Names
Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
Protein Family
Protein lifeguard
UniProt Gene Name
FAIM2
UniProt Synonym Gene Names
KIAA0950; LFG; LFG2; NMP35; TMBIM2
UniProt Entry Name
LFG2_HUMAN
NCBI Protein Information
protein lifeguard 2; neural membrane protein 35; transmembrane BAX inhibitor motif-containing protein 2

UniProt Comments for FAIM2

FAIM2: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. Belongs to the BI1 family. LFG subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Apoptosis

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: postsynaptic membrane; integral to membrane; cell junction; lipid raft

Biological Process: apoptosis; cerebellar granular layer development; regulation of neuron apoptosis; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell layer development; cerebellum development; negative regulation of neuron apoptosis; negative regulation of apoptosis
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Research Articles on FAIM2

1. This study highlighted the importance of two candidate genes, SH2B1 and FAIM2, in the risk of overweight/obesity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FAIM2 antibody

 Reference Product  PubMed Publications
 GNPDA2 antibody  >21 publications with FAIM2 and GNPDA2
 SH2B1 antibody  >19 publications with FAIM2 and SH2B1
 TMEM18 antibody  >19 publications with FAIM2 and TMEM18
 KCTD15 antibody  >18 publications with FAIM2 and KCTD15
 SEC16B antibody  >17 publications with FAIM2 and SEC16B
 FAS antibody  >16 publications with FAIM2 and FAS
 MTCH2 antibody  >13 publications with FAIM2 and MTCH2
 BCDIN3D antibody  >3 publications with FAIM2 and BCDIN3D
 FADD antibody  >3 publications with FAIM2 and FADD
 BAX antibody  >3 publications with FAIM2 and BAX

Pathways associated with anti-FAIM2 antibody

 Products by Pathway  Pathway Diagram
 FAS (CD95) Signaling Pathway antibodies  FAS (CD95) Signaling Pathway Diagram

Diseases associated with anti-FAIM2 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5 publications with FAIM2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >3 publications with FAIM2 and Disease Models, Animal
 Hypertension Antibodies  >2 publications with FAIM2 and Hypertension
 Breast Neoplasms Antibodies  >2 publications with FAIM2 and Breast Neoplasms
 Brain Ischemia Antibodies  >2 publications with FAIM2 and Brain Ischemia
 Heart Diseases Antibodies  >2 publications with FAIM2 and Heart Diseases
 Gonadal Disorders Antibodies  >1 publications with FAIM2 and Gonadal Disorders
 Arteriosclerosis Antibodies  >1 publications with FAIM2 and Arteriosclerosis
 Lung Diseases Antibodies  >1 publications with FAIM2 and Lung Diseases
 Weight Gain Antibodies  >1 publications with FAIM2 and Weight Gain

Organs/Tissues associated with anti-FAIM2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with FAIM2 and Brain
 Nerve Antibodies  >6 publications with FAIM2 and Nerve
 Kidney Antibodies  >1 publications with FAIM2 and Kidney
 Ovary Antibodies  >1 publications with FAIM2 and Ovary
 Muscle Antibodies  >1 publications with FAIM2 and Muscle
 Heart Antibodies  >1 publications with FAIM2 and Heart
 Pancreas Antibodies  >1 publications with FAIM2 and Pancreas
 Eye Antibodies  >1 publications with FAIM2 and Eye
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