• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

BICD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150672

BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BICD1, Polyclonal Antibody
Full Product Name
BICD1 Antibody
Product Gene Name
anti-BICD1 antibody
Product Synonym Names
BICD1; BICD; Protein bicaudal D homolog 1; Bic-D 1; bicaudal D homolog 1 (Drosophila)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
BICD1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.
Preparation and Storage
BICD1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
BICD1 peptide (MBS151854) is used for blocking the activity of BICD1 antibody (MBS150672)
Molecular Weight
95,739 Da
OMIM
602204
3D Structure
ModBase 3D Structure for Q96G01
Conjugate
Unconjugated
Immunogen
BICD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BICD1.
Buffer
BICD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-BICD1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-BICD1 antibody
BICD1 antibody can be used for detection of BICD1 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 10 mug/mL.

Western Blot (WB) of anti-BICD1 antibody

Western blot analysis of BICD1 in Daudi cell lysate with BICD1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-BICD1 Polyclonal Antibody – Cat# MBS150672

Immunocytochemistry (IHC) of anti-BICD1 antibody

Immunocytochemistry of BICD1 in Daudi cells with BICD1 antibody at 2.5 μg/mL.
Rabbit Anti-BICD1 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150672

Immunofluorescence (IF) of anti-BICD1 antibody

Immunofluorescence of BICD1 in Daudi cells with BICD1 antibody at 20 μg/mL.
Rabbit Anti-BICD1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150672

Other Notes

Small volumes of anti-BICD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BICD1 purchase

MBS150672 is an antibody targeting BICD1. Also known as BICD1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BICD1. It may not necessarily be applicable to this product.

NCBI GI #
51039802
NCBI GeneID
636
NCBI Accession #
NP_001705
UniProt Primary Accession #
Q96G01
UniProt Secondary Accession #
O43892; O43893; A8K2C3; F8W113
UniProt Related Accession #
Q96G01
GenBank Nucleotide #
NM_001714.2
NCBI Official Full Name
protein bicaudal D homolog 1 isoform 1
NCBI Official Synonym Full Names
bicaudal D homolog 1 (Drosophila)
NCBI Official Symbol
BICD1
NCBI Official Synonym Symbols
BICD
UniProt Protein Name
Protein bicaudal D homolog 1
Protein Family
Protein bicaudal
UniProt Gene Name
BICD1
UniProt Synonym Gene Names
Bic-D 1
UniProt Entry Name
BICD1_HUMAN
NCBI Protein Information
protein bicaudal D homolog 1; bic-D 1; cytoskeleton-like bicaudal D protein homolog 1

NCBI Summary for BICD1

This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for BICD1

BICD1: Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. Belongs to the BicD family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 12p11.2-p11.1

Cellular Component: Golgi apparatus; cytoskeleton; membrane; cytoplasmic microtubule; perinuclear region of cytoplasm; tubulin complex; cytoplasmic vesicle; trans-Golgi network; cytosol

Molecular Function: dynein binding; protein binding; proteinase activated receptor binding; structural constituent of cytoskeleton; cytoskeletal adaptor activity; Rab GTPase binding

Biological Process: RNA processing; stress granule assembly; intracellular mRNA localization; anatomical structure morphogenesis; viral reproduction; protein localization in organelle; positive regulation of receptor-mediated endocytosis
Show more

Research Articles on BICD1

1. Variants in BICD1 are associated with length of telomeres, which suggests that a mechanism linked to accelerated aging may be involved in the pathogenesis of emphysema.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BICD1 antibody

 Reference Product  PubMed Publications
 RAB6A antibody  >2 publications with BICD1 and RAB6A

Diseases associated with anti-BICD1 antibody

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >2 publications with BICD1 and Heart Diseases
 Inflammation Antibodies  >1 publications with BICD1 and Inflammation
 Breast Neoplasms Antibodies  >1 publications with BICD1 and Breast Neoplasms

Organs/Tissues associated with anti-BICD1 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >5 publications with BICD1 and Heart
 Brain Antibodies  >5 publications with BICD1 and Brain
 Lung Antibodies  >3 publications with BICD1 and Lung
 Blood Antibodies  >3 publications with BICD1 and Blood
 Intestine Antibodies  >1 publications with BICD1 and Intestine
 Muscle Antibodies  >1 publications with BICD1 and Muscle
 Kidney Antibodies  >1 publications with BICD1 and Kidney
 Embryonic Tissue Antibodies  >1 publications with BICD1 and Embryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000