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MATN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150676

MATN1 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MATN1, Polyclonal Antibody
Full Product Name
MATN1 Antibody
Product Gene Name
anti-MATN1 antibody
Product Synonym Names
MATN1; CMP; CRTM; CMP; Cartilage matrix protein; Matrilin-1; matrilin 1, cartilage matrix protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
MATN1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
MATN1 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
MATN1 peptide (MBS152402) is used for blocking the activity of MATN1 antibody (MBS150676)
Molecular Weight
53,701 Da
OMIM
115437
3D Structure
ModBase 3D Structure for P21941
Conjugate
Unconjugated
Immunogen
MATN1 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN1.
Buffer
MATN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-MATN1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-MATN1 antibody
MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-MATN1 antibody

Western blot analysis of MATN1 in rat liver tissue lysate with MATN1 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-MATN1 Polyclonal Antibody – Cat# MBS150676

Immunohistochemistry (IHC) of anti-MATN1 antibody

Immunohistochemistry of MATN1 in human liver tissue with MATN1 antibody at 5 μg/mL.
Rabbit Anti-MATN1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150676

Immunofluorescence (IF) of anti-MATN1 antibody

Immunofluorescence of MATN1 in Human Liver cells with MATN1 antibody at 20 μg/mL.
Rabbit Anti-MATN1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150676

Other Notes

Small volumes of anti-MATN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MATN1 purchase

MBS150676 is an antibody targeting MATN1. Also known as MATN1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MATN1. It may not necessarily be applicable to this product.

NCBI GI #
4505111
NCBI GeneID
4146
NCBI Accession #
NP_002370
UniProt Primary Accession #
P21941
UniProt Secondary Accession #
Q5TBB9; B2R7E3
UniProt Related Accession #
P21941
GenBank Nucleotide #
NM_002379.3
NCBI Official Full Name
cartilage matrix protein
NCBI Official Synonym Full Names
matrilin 1, cartilage matrix protein
NCBI Official Symbol
MATN1
NCBI Official Synonym Symbols
CMP; CRTM
UniProt Protein Name
Cartilage matrix protein
UniProt Synonym Protein Names
Matrilin-1
Protein Family
Cartilage matrix protein
UniProt Gene Name
MATN1
UniProt Synonym Gene Names
CMP; CRTM
UniProt Entry Name
MATN1_HUMAN
NCBI Protein Information
cartilage matrix protein

NCBI Summary for MATN1

This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq, Jul 2008]
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UniProt Comments for MATN1

MATN1: Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p35

Cellular Component: proteinaceous extracellular matrix; extracellular region

Molecular Function: protein binding; extracellular matrix structural constituent

Biological Process: extracellular matrix organization and biogenesis; protein complex assembly; regulation of bone mineralization
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Research Articles on MATN1

1. Matrilin-1 is an inhibitor of neovascularization

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MATN1 antibody

 Reference Product  PubMed Publications
 COMP antibody  >68 publications with MATN1 and COMP
 MATN3 antibody  >20 publications with MATN1 and MATN3
 MATN2 antibody  >10 publications with MATN1 and MATN2
 MATN4 antibody  >7 publications with MATN1 and MATN4
 COL2A1 antibody  >7 publications with MATN1 and COL2A1

Pathways associated with anti-MATN1 antibody

 Products by Pathway  Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram

Diseases associated with anti-MATN1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with MATN1 and Inflammation
 Necrosis Antibodies  >4 publications with MATN1 and Necrosis
 Fibrosis Antibodies  >2 publications with MATN1 and Fibrosis
 Heart Diseases Antibodies  >2 publications with MATN1 and Heart Diseases
 Cardiomyopathies Antibodies  >1 publications with MATN1 and Cardiomyopathies
 Breast Neoplasms Antibodies  >1 publications with MATN1 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with MATN1 and Neoplasm Metastasis
 Hyperplasia Antibodies  >1 publications with MATN1 and Hyperplasia
 Atherosclerosis Antibodies  >1 publications with MATN1 and Atherosclerosis
 Carcinoma Antibodies  >1 publications with MATN1 and Carcinoma

Organs/Tissues associated with anti-MATN1 antibody

 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >48 publications with MATN1 and Connective Tissue
 Blood Antibodies  >22 publications with MATN1 and Blood
 Embryonic Tissue Antibodies  >17 publications with MATN1 and Embryonic Tissue
 Eye Antibodies  >9 publications with MATN1 and Eye
 Trachea Antibodies  >7 publications with MATN1 and Trachea
 Kidney Antibodies  >4 publications with MATN1 and Kidney
 Uterus Antibodies  >1 publications with MATN1 and Uterus
 Brain Antibodies  >1 publications with MATN1 and Brain
 Placenta Antibodies  >1 publications with MATN1 and Placenta
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