• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TMEM59L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150749

TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TMEM59L, Polyclonal Antibody
Full Product Name
TMEM59L Antibody
Product Gene Name
Product Synonym Names
TMEM59L; BSMAP; C19orf4; BSMAP; Transmembrane protein 59-like; Brain-specific membrane-anchored protein; transmembrane protein 59-like
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
TMEM59L Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
TMEM59L peptide (MBS152107) is used for blocking the activity of TMEM59L antibody (MBS150749)
Molecular Weight
37,619 Da
3D Structure
ModBase 3D Structure for Q9UK28
Conjugate
Unconjugated
Immunogen
TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L.
Buffer
TMEM59L Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TMEM59L antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TMEM59L antibody
TMEM59L antibody can be used for detection of TMEM59L by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-TMEM59L antibody

Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 μg/mL.
Rabbit Anti-TMEM59L Polyclonal Antibody – Cat# MBS150749

Immunohistochemistry (IHC) of anti-TMEM59L antibody

Immunohistochemistry of TMEM59L in mouse brain tissue with TMEM59L antibody at 2.5 μg/mL.
Rabbit Anti-TMEM59L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150749

Immunofluorescence (IF) of anti-TMEM59L antibody

Immunofluorescence of TMEM59L in mouse brain tissue with TMEM59L antibody at 20 μg/mL.
Rabbit Anti-TMEM59L Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150749

Other Notes

Small volumes of anti-TMEM59L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMEM59L purchase

MBS150749 is an antibody targeting TMEM59L. Also known as TMEM59L Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM59L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane protein 59-like
NCBI Official Synonym Full Names
transmembrane protein 59-like
NCBI Official Symbol
TMEM59L
NCBI Official Synonym Symbols
BSMAP; C19orf4
UniProt Protein Name
Transmembrane protein 59-like
UniProt Synonym Protein Names
Brain-specific membrane-anchored protein
Protein Family
UniProt Gene Name
TMEM59L
UniProt Synonym Gene Names
BSMAP; C19orf4
UniProt Entry Name
TM59L_HUMAN
NCBI Protein Information
transmembrane protein 59-like; brain-specific membrane-anchored protein

NCBI Summary for TMEM59L

This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]

UniProt Comments for TMEM59L

TMEM59L: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p12

Cellular Component: Golgi membrane; membrane; integral to membrane
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TMEM59L antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with TMEM59L and Necrosis

Organs/Tissues associated with anti-TMEM59L antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with TMEM59L and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000