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SYTL5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150760

SYTL5 Antibody: SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is… More details

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Product Overview

Online Datasheet in PDF
Product Name
SYTL5, Polyclonal Antibody
Full Product Name
SYTL5 Antibody
Product Gene Name
Product Synonym Names
SYTL5; slp5; SLP5; Synaptotagmin-like protein 5; synaptotagmin-like 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
SYTL5 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.
Preparation and Storage
SYTL5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SYTL5 peptide (MBS152828) is used for blocking the activity of SYTL5 antibody (MBS150760)
Molecular Weight
83,918 Da
3D Structure
ModBase 3D Structure for Q8TDW5
Conjugate
Unconjugated
Immunogen
SYTL5 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SYTL5.
Buffer
SYTL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SYTL5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SYTL5 antibody
SYTL5 antibody can be used for detection of SYTL5 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL.

Western Blot (WB) of anti-SYTL5 antibody

Western blot analysis of SYTL5 in Hela cell lysate with SYTL5 antibody at (A) 1 and (B) 2 μg/mL .
Rabbit Anti-SYTL5 Polyclonal Antibody – Cat# MBS150760

Immunohistochemistry (IHC) of anti-SYTL5 antibody

Immunohistochemistry of SYTL2 in rat liver tissue with SYTL2 antibody at 5 μg/mL.
Rabbit Anti-SYTL5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150760

Other Notes

Small volumes of anti-SYTL5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYTL5 purchase

MBS150760 is an antibody targeting SYTL5. Also known as SYTL5 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYTL5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
synaptotagmin-like protein 5 isoform 1
NCBI Official Synonym Full Names
synaptotagmin-like 5
NCBI Official Symbol
SYTL5
NCBI Official Synonym Symbols
slp5
UniProt Protein Name
Synaptotagmin-like protein 5
UniProt Gene Name
SYTL5
UniProt Synonym Gene Names
SLP5
UniProt Entry Name
SYTL5_HUMAN
NCBI Protein Information
synaptotagmin-like protein 5; exophilin 9

NCBI Summary for SYTL5

The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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UniProt Comments for SYTL5

SYTL5: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: membrane

Molecular Function: protein binding; metal ion binding; Rab GTPase binding

Biological Process: intracellular protein transport; exocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SYTL5 antibody

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with SYTL5 and Fibrosis
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