• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TCTN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150796

TCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TCTN3, Polyclonal Antibody
Full Product Name
TCTN3 Antibody
Product Gene Name
Product Synonym Names
TCTN3; OFD4; TECT3; JBTS18; C10orf61; PSEC0041; UNQ1881/PRO4324; Tectonic-3; tectonic family member 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
TCTN3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
TCTN3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
TCTN3 peptide (MBS152750) is used for blocking the activity of TCTN3 antibody (MBS150796)
Molecular Weight
50,258 Da
OMIM
gene 614815
3D Structure
ModBase 3D Structure for Q6NUS6
Conjugate
Unconjugated
Immunogen
TCTN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TCTN3.
Buffer
TCTN3 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TCTN3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TCTN3 antibody
TCTN3 antibody can be used for detection of TCTN3 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 4 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-TCTN3 antibody

Western blot analysis of TCTN3 in HeLa cell lysate with TCTN3 antibody at (A) 1 and (B) 2μg/mL.
Rabbit Anti-TCTN3 Polyclonal Antibody – Cat# MBS150796

Immunocytochemistry (IHC) of anti-TCTN3 antibody

Immunocytochemistry of TCTN3 in HeLa cells with TCTN3 antibody at 4 μg/mL.
Rabbit Anti-TCTN3 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150796

Immunofluorescence (IF) of anti-TCTN3 antibody

Immunofluorescence of TCTN3 in HeLa cells with TCTN3 antibody at 20 μg/mL.
Rabbit Anti-TCTN3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150796

Other Notes

Small volumes of anti-TCTN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCTN3 purchase

MBS150796 is an antibody targeting TCTN3. Also known as TCTN3 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TCTN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tectonic-3 isoform a
NCBI Official Synonym Full Names
tectonic family member 3
NCBI Official Symbol
TCTN3
NCBI Official Synonym Symbols
OFD4; TECT3; JBTS18; C10orf61
UniProt Protein Name
Tectonic-3
Protein Family
UniProt Gene Name
TCTN3
UniProt Synonym Gene Names
C10orf61; TECT3
UniProt Entry Name
TECT3_HUMAN
NCBI Protein Information
tectonic-3

NCBI Summary for TCTN3

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]
Show more

UniProt Comments for TCTN3

TCTN3: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation. Belongs to the tectonic family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 10q24.1

Cellular Component: integral to membrane

Biological Process: smoothened signaling pathway; apoptosis; organelle organization and biogenesis

Disease: Joubert Syndrome 18; Joubert Syndrome 1; Orofaciodigital Syndrome Iv
Show more

Research Articles on TCTN3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000