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SYNPO2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150803

SYNPO2 Antibody: SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SYNPO2, Polyclonal Antibody
Full Product Name
SYNPO2 Antibody
Product Gene Name
anti-SYNPO2 antibody
Product Synonym Names
SYNPO2; Synaptopodin-2; Genethonin-2; synaptopodin 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
SYNPO2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
SYNPO2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SYNPO2 peptide (MBS152451) is used for blocking the activity of SYNPO2 antibody (MBS150803)
Molecular Weight
133,081 Da
3D Structure
ModBase 3D Structure for Q9UMS6
Conjugate
Unconjugated
Immunogen
SYNPO2 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human SYNPO2.
Buffer
SYNPO2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SYNPO2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SYNPO2 antibody
SYNPO2 antibody can be used for detection of SYNPO2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SYNPO2 antibody

Western blot analysis of SYNPO2 in human skeletal muscle tissue lysate with SYNPO2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-SYNPO2 Polyclonal Antibody – Cat# MBS150803

Immunohistochemistry (IHC) of anti-SYNPO2 antibody

Immunohistochemistry of SYNPO2 in mouse skeletal muscle tissue with SYNPO2 antibody at 5 μg/mL.
Rabbit Anti-SYNPO2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150803

Immunofluorescence (IF) of anti-SYNPO2 antibody

Immunofluorescence of SYNPO2 in mouse skeletal muscle tissue with SYNPO2 antibody at 20 μg/mL.
Rabbit Anti-SYNPO2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150803

Other Notes

Small volumes of anti-SYNPO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYNPO2 purchase

MBS150803 is an antibody targeting SYNPO2. Also known as SYNPO2 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYNPO2. It may not necessarily be applicable to this product.

NCBI GI #
193083183
NCBI GeneID
171024
NCBI Accession #
NP_597734
UniProt Primary Accession #
Q9UMS6
UniProt Secondary Accession #
Q9UK89; B2RWP6; B2Y8J9; S5XAM4
UniProt Related Accession #
Q9UMS6
GenBank Nucleotide #
NM_133477.2
NCBI Official Full Name
synaptopodin-2 isoform a
NCBI Official Synonym Full Names
synaptopodin 2
NCBI Official Symbol
SYNPO2
UniProt Protein Name
Synaptopodin-2
UniProt Synonym Protein Names
Genethonin-2; Myopodin
Protein Family
Synaptopodin
UniProt Gene Name
SYNPO2
UniProt Entry Name
SYNP2_HUMAN
NCBI Protein Information
synaptopodin-2; myopodin; genethonin-2

UniProt Comments for SYNPO2

SYNPO2: Has an actin-binding and actin-bundling activity. Belongs to the synaptopodin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 4q26

Cellular Component: focal adhesion; Z disc; nucleus; actin cytoskeleton

Molecular Function: protein binding; actin binding; muscle alpha-actinin binding
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Research Articles on SYNPO2

1. myopodin is epigenetically modified in colon cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SYNPO2 antibody

 Reference Product  PubMed Publications
 ILK antibody  >1 publications with SYNPO2 and ILK
 ZYX antibody  >1 publications with SYNPO2 and ZYX

Diseases associated with anti-SYNPO2 antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >4 publications with SYNPO2 and Neoplasm Metastasis
 Nervous System Diseases Antibodies  >2 publications with SYNPO2 and Nervous System Diseases
 Necrosis Antibodies  >2 publications with SYNPO2 and Necrosis
 Congenital Abnormalities Antibodies  >1 publications with SYNPO2 and Congenital Abnormalities

Organs/Tissues associated with anti-SYNPO2 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >14 publications with SYNPO2 and Muscle
 Prostate Antibodies  >11 publications with SYNPO2 and Prostate
 Heart Antibodies  >4 publications with SYNPO2 and Heart
 Lung Antibodies  >2 publications with SYNPO2 and Lung
 Embryonic Tissue Antibodies  >2 publications with SYNPO2 and Embryonic Tissue
 Blood Antibodies  >1 publications with SYNPO2 and Blood
 Connective Tissue Antibodies  >1 publications with SYNPO2 and Connective Tissue
 Stomach Antibodies  >1 publications with SYNPO2 and Stomach
 Brain Antibodies  >1 publications with SYNPO2 and Brain
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