Rabbit Anti-FNIP2 Polyclonal Antibody – Cat# MBS150813

Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 μg/mL.

FNIP2 Antibody – Rabbit Polyclonal

Name: FNIP2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS150813
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150813

FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FNIP2, Polyclonal Antibody

Full Product Name

FNIP2 Antibody

Product Gene Name

anti-FNIP2 antibody

Product Synonym Names

FNIP2; FNIPL; MAPO1; FNIPL; KIAA1450; Folliculin-interacting protein 2; FNIP1-like protein; folliculin interacting protein 2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid

Purity/Purification

FNIP2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL (lot specific)

Specificity

Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.

Preparation and Storage

FNIP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antibody/Peptide Pairs

FNIP2 peptide (MBS152432) is used for blocking the activity of FNIP2 antibody (MBS150813)

Molecular Weight

124,860 Da

OMIM

612768

3D Structure

ModBase 3D Structure for Q9P278

Conjugate

Unconjugated

Immunogen

FNIP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human FNIP2.

Buffer

FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Applications Tested/Suitable for anti-FNIP2 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-FNIP2 antibody

FNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 mug/mL.

Other Notes

Small volumes of anti-FNIP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FNIP2 purchase

MBS150813 is an antibody targeting FNIP2. Also known as FNIP2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FNIP2. It may not necessarily be applicable to this product.

NCBI GI #

154689769

NCBI GeneID

57600

NCBI Accession #

NP_065891

UniProt Primary Accession #

Q9P278

UniProt Secondary Accession #

Q05DC3; Q96I31; Q9H994

UniProt Related Accession #

Q9P278

GenBank Nucleotide #

NM_020840.1

NCBI Official Full Name

folliculin-interacting protein 2

NCBI Official Synonym Full Names

folliculin interacting protein 2

NCBI Official Symbol

FNIP2

NCBI Official Synonym Symbols

FNIPL; MAPO1

UniProt Protein Name

Folliculin-interacting protein 2

UniProt Synonym Protein Names

FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein

Protein Family

Folliculin-interacting protein

UniProt Gene Name

FNIP2

UniProt Synonym Gene Names

FNIPL; KIAA1450; MAPO1

UniProt Entry Name

FNIP2_HUMAN

NCBI Protein Information

folliculin-interacting protein 2; FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein

UniProt Comments for FNIP2

FNIP2: May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Belongs to the FNIP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 4q32.1

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center

Molecular Function: protein binding

Biological Process: regulation of protein amino acid phosphorylation; DNA damage response, signal transduction resulting in induction of apoptosis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation; protein amino acid phosphorylation

Research Articles on FNIP2

1. this study obtained evidence to show that stabilization of MAPO1 is regulated through its specific interaction with folliculin and AMPK.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FNIP2 antibody

Reference Product	PubMed Publications
FLCN antibody	>11 publications with FNIP2 and FLCN

Diseases associated with anti-FNIP2 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>3 publications with FNIP2 and Kidney Diseases

Organs/Tissues associated with anti-FNIP2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>4 publications with FNIP2 and Kidney
Lung Antibodies	>2 publications with FNIP2 and Lung
Nerve Antibodies	>1 publications with FNIP2 and Nerve
Brain Antibodies	>1 publications with FNIP2 and Brain