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EIG121 (EGI) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150850

EIG121 Antibody: EIG121 (Estrogen-induced gene 121 protein) is thought to play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family. It is a 1013 amino acid single-pass transmembrane… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
EIG121 (EGI), Polyclonal Antibody
Full Product Name
EIG121 Antibody
Product Gene Name
Product Synonym Names
EIG121; EIG; EIG1; epilepsy, generalized, idiopathic
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
EIG121 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.
Preparation and Storage
EIG121 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
EIG121 peptide (MBS152463) is used for blocking the activity of EIG121 antibody (MBS150850)
Molecular Weight
110,416 Da
OMIM
611298
3D Structure
ModBase 3D Structure for Q6UXG2
Conjugate
Unconjugated
Immunogen
EIG121 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human EIG121.
Buffer
EIG121 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-EGI antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-EGI antibody
EIG121 antibody can be used for detection of EIG121 by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-EGI antibody

Western blot analysis of EIG121 in MCF7 cell lysate with EIG121 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-EGI Polyclonal Antibody – Cat# MBS150850

Immunocytochemistry (IHC) of anti-EGI antibody

Immunocytochemistry of EIG121 in MCF7 cells with EIG121 antibody at 5 μg/mL.
Rabbit Anti-EGI Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150850

Immunofluorescence (IF) of anti-EGI antibody

Immunofluorescence of EIG121 in MCF7 cells with EIG121 antibody at 20 μg/mL.
Rabbit Anti-EGI Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150850

Other Notes

Small volumes of anti-EGI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGI purchase

MBS150850 is an antibody targeting EGI. Also known as EIG121 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EGI. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
UPF0577 protein KIAA1324 isoform 1
NCBI Official Synonym Full Names
KIAA1324
NCBI Official Symbol
KIAA1324
NCBI Official Synonym Symbols
EIG121
UniProt Protein Name
UPF0577 protein KIAA1324
UniProt Synonym Protein Names
Estrogen-induced gene 121 protein
UniProt Gene Name
KIAA1324
UniProt Synonym Gene Names
EIG121
UniProt Entry Name
K1324_HUMAN
NCBI Protein Information
UPF0577 protein KIAA1324; maba1; estrogen-induced gene 121 protein

NCBI Summary for EGI

Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
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UniProt Comments for EGI

KIAA1324: May play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. Belongs to the UPF0577 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: late endosome membrane; lysosome; integral to plasma membrane; lysosomal membrane; late endosome; trans-Golgi network

Biological Process: macroautophagy; cellular response to starvation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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