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BIRC8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150864

ILP-2 Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ILP-2 (BIRC8), Polyclonal Antibody
Full Product Name
ILP-2 Antibody
Product Gene Name
anti-BIRC8 antibody
Product Synonym Names
ILP-2; ILP2; ILP-2; hILP2; ILP2; Baculoviral IAP repeat-containing protein 8; Inhibitor of apoptosis-like protein 2; IAP-like protein 2; baculoviral IAP repeat-containing 8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
ILP-2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
ILP-2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ILP-2 peptide (MBS152666) is used for blocking the activity of ILP-2 antibody (MBS150864)
Molecular Weight
33 kDa
3D Structure
ModBase 3D Structure for Q96P09
Conjugate
Unconjugated
Immunogen
ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.
Buffer
ILP-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-BIRC8 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-BIRC8 antibody
ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1 mug/mL. A band at approximately 33 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-BIRC8 antibody

Western blot analysis of ILP-2 expression in human HepG2 (lane 1) and MOLT4 (lane 2) cell lysates with ILP-2 antibody at 1 μg/mL.
Rabbit Anti-BIRC8 Polyclonal Antibody – Cat# MBS150864

Immunocytochemistry (IHC) of anti-BIRC8 antibody

Immunocytochemistry of ILP-2 in HepG2 cells with ILP-2 antibody at 10 μg/mL.
Rabbit Anti-BIRC8 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS150864

Immunofluorescence (IF) of anti-BIRC8 antibody

Immunofluorescence of ILP-2 in HepG2 cells with ILP-2 antibody at 20 μg/mL.
Rabbit Anti-BIRC8 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150864

Other Notes

Small volumes of anti-BIRC8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BIRC8 purchase

MBS150864 is an antibody targeting BIRC8. Also known as ILP-2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BIRC8. It may not necessarily be applicable to this product.

NCBI GI #
44680139
NCBI GeneID
112401
NCBI Accession #
NP_203127
UniProt Primary Accession #
Q96P09
UniProt Secondary Accession #
Q6IPY1; Q96RW5
UniProt Related Accession #
Q96P09
GenBank Nucleotide #
NM_033341.4
NCBI Official Full Name
baculoviral IAP repeat-containing protein 8
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 8
NCBI Official Symbol
BIRC8
NCBI Official Synonym Symbols
ILP2; ILP-2; hILP2
UniProt Protein Name
Baculoviral IAP repeat-containing protein 8
UniProt Synonym Protein Names
Inhibitor of apoptosis-like protein 2; IAP-like protein 2; ILP-2; Testis-specific inhibitor of apoptosis
Protein Family
Baculoviral IAP repeat-containing protein
UniProt Gene Name
BIRC8
UniProt Synonym Gene Names
ILP2; IAP-like protein 2; ILP-2
UniProt Entry Name
BIRC8_HUMAN
NCBI Protein Information
baculoviral IAP repeat-containing protein 8; IAP-like protein 2; baculoviral IAP repeat-containing 8; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis

UniProt Comments for BIRC8

BIRC8: Protects against apoptosis mediated by BAX. Belongs to the IAP family.

Protein type: Ubiquitin conjugating system; Apoptosis

Chromosomal Location of Human Ortholog: -

Cellular Component: spindle microtubule; perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol

Molecular Function: protease binding; zinc ion binding; caspase inhibitor activity; ubiquitin-protein ligase activity

Biological Process: neuron apoptosis; protein ubiquitination; negative regulation of neuron apoptosis; negative regulation of apoptosis
Show more

Research Articles on BIRC8

1. increased expression with progression of chronic myeloid leukaemia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BIRC8 antibody

 Reference Product  PubMed Publications
 BIRC5 antibody  >4 publications with BIRC8 and BIRC5
 CASP9 antibody  >4 publications with BIRC8 and CASP9
 APAF1 antibody  >2 publications with BIRC8 and APAF1
 DIABLO antibody  >1 publications with BIRC8 and DIABLO

Pathways associated with anti-BIRC8 antibody

 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Small Cell Lung Cancer Pathway antibodies  Small Cell Lung Cancer Pathway Diagram
 Small Cell Lung Cancer Pathway antibodies  Small Cell Lung Cancer Pathway Diagram
 Toxoplasmosis Pathway antibodies  Toxoplasmosis Pathway Diagram
 Toxoplasmosis Pathway antibodies  Toxoplasmosis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram

Diseases associated with anti-BIRC8 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >2 publications with BIRC8 and Kidney Diseases
 Necrosis Antibodies  >1 publications with BIRC8 and Necrosis
 Nervous System Diseases Antibodies  >1 publications with BIRC8 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with BIRC8 and Disease Models, Animal
 Acute Kidney Injury Antibodies  >1 publications with BIRC8 and Acute Kidney Injury

Organs/Tissues associated with anti-BIRC8 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >4 publications with BIRC8 and Testis
 Brain Antibodies  >1 publications with BIRC8 and Brain
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