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FKBP15 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS150935

FKBP15 Antibody: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FKBP15, Polyclonal Antibody
Full Product Name
FKBP15 Antibody
Product Gene Name
anti-FKBP15 antibody
Product Synonym Names
FKBP15; FKBP133; PPP1R76; KIAA0674; FK506-binding protein 15; 133 kDa FK506-binding protein; FKBP-15; FK506 binding protein 15, 133kDa
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
FKBP15 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
FKBP15 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
FKBP15 peptide (MBS152393) is used for blocking the activity of FKBP15 antibody (MBS150935)
Molecular Weight
50,330 Da
3D Structure
ModBase 3D Structure for Q5T1M5
Conjugate
Unconjugated
Immunogen
FKBP15 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FKBP15.
Buffer
FKBP15 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-FKBP15 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-FKBP15 antibody
FKBP15 antibody can be used for detection of FKBP15 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-FKBP15 antibody

Western blot analysis of FKBP15 in 3T3 cell lysate with FKBP15 antibody at 1 μg/mL.
Rabbit Anti-FKBP15 Polyclonal Antibody – Cat# MBS150935

Immunohistochemistry (IHC) of anti-FKBP15 antibody

Immunohistochemistry of FKBP15 in mouse brain tissue with FKBP15 antibody at 2.5 μg/mL.
Rabbit Anti-FKBP15 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS150935

Immunofluorescence (IF) of anti-FKBP15 antibody

Immunofluorescence of FKBP15 in mouse brain tissue with FKBP15 antibody at 20 μg/mL.
Rabbit Anti-FKBP15 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS150935

Other Notes

Small volumes of anti-FKBP15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FKBP15 purchase

MBS150935 is an antibody targeting FKBP15. Also known as FKBP15 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FKBP15. It may not necessarily be applicable to this product.

NCBI GI #
150010552
NCBI GeneID
23307
NCBI Accession #
NP_056073
UniProt Primary Accession #
Q5T1M5
UniProt Secondary Accession #
Q05DK8; Q5T1M2; Q6DD85; Q9Y4D0
UniProt Related Accession #
Q5T1M5
GenBank Nucleotide #
NM_015258.1
NCBI Official Full Name
FK506-binding protein 15
NCBI Official Synonym Full Names
FK506 binding protein 15, 133kDa
NCBI Official Symbol
FKBP15
NCBI Official Synonym Symbols
FKBP133; PPP1R76; KIAA0674
UniProt Protein Name
FK506-binding protein 15
UniProt Synonym Protein Names
133 kDa FK506-binding protein; 133 kDa FKBP; FKBP-133; WASP and FKBP-like; WAFL
Protein Family
FK506-binding protein
UniProt Gene Name
FKBP15
UniProt Synonym Gene Names
KIAA0674; FKBP-15; 133 kDa FKBP; FKBP-133; WAFL
UniProt Entry Name
FKB15_HUMAN
NCBI Protein Information
FK506-binding protein 15; WAFL; FKBP-15; FKBP-133; 133 kDa FKBP; WASP and FKBP-like protein; FK506-binding protein 133kDa; 133 kDa FK506-binding protein; protein phosphatase 1, regulatory subunit 76

UniProt Comments for FKBP15

FKBP15: May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase. Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule- based movement. Belongs to the FKBP-type PPIase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: growth cone; membrane; axon; early endosome; actin filament

Molecular Function: protein binding; actin binding

Biological Process: protein folding; endocytosis
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Research Articles on FKBP15

1. findings are compatible with a model whereby WAFL is involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FKBP15 antibody

 Reference Product  PubMed Publications
 KIAA1033 antibody  >1 publications with FKBP15 and KIAA1033
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