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SYNPO Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151009

SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SYNPO, Polyclonal Antibody
Full Product Name
SYNPO Antibody
Product Gene Name
Product Synonym Names
SYNPO; KIAA1029; Synaptopodin; synaptopodin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
SYNPO Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SYNPO peptide (MBS152993) is used for blocking the activity of SYNPO antibody (MBS151009)
Molecular Weight
73,667 Da
OMIM
608155
3D Structure
ModBase 3D Structure for Q8N3V7
Conjugate
Unconjugated
Immunogen
SYNPO antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO.
Buffer
SYNPO Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SYNPO antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SYNPO antibody
SYNPO antibody can be used for detection of SYNPO by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SYNPO antibody

Western blot analysis of SYNPO in rat brain tissue lysate with SYNPO antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-SYNPO Polyclonal Antibody – Cat# MBS151009

Immunohistochemistry (IHC) of anti-SYNPO antibody

Immunohistochemistry of SYNPO in human brain tissue with SYNPO antibody at 2.5 μg/mL.
Rabbit Anti-SYNPO Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151009

Immunofluorescence (IF) of anti-SYNPO antibody

Immunofluorescence of SYNPO in human brain tissue with SYNPO antibody at 20 μg/mL.
Rabbit Anti-SYNPO Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151009

Immunofluorescence (IF) of anti-SYNPO antibody

Immunofluorescence of SYNPO in mouse brain tissue with SYNPO antibody at 20 μg/mL.

Red: SYNPO Antibody (6049)
Blue: DAPI staining
Rabbit Anti-SYNPO Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151009

Immunohistochemistry (IHC) of anti-SYNPO antibody

Immunohistochemistry of SYNPO in mouse brain tissue with SYNPO antibody at 5 μg/mL.
Rabbit Anti-SYNPO Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151009

Other Notes

Small volumes of anti-SYNPO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYNPO purchase

MBS151009 is an antibody targeting SYNPO. Also known as SYNPO Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYNPO. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
synaptopodin isoform C
NCBI Official Synonym Full Names
synaptopodin
NCBI Official Symbol
SYNPO
UniProt Protein Name
Synaptopodin
Protein Family
UniProt Gene Name
SYNPO
UniProt Synonym Gene Names
KIAA1029
UniProt Entry Name
SYNPO_HUMAN
NCBI Protein Information
synaptopodin

NCBI Summary for SYNPO

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SYNPO

SYNPO: an actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.

Protein type: Actin-binding; Cytoskeletal

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: postsynaptic membrane; tight junction; postsynaptic density; cytoplasm; dendritic spine; stress fiber; perikaryon; actin cytoskeleton

Molecular Function: protein binding; actin binding

Biological Process: regulation of stress fiber formation; positive regulation of actin filament bundle formation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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