Rabbit Anti-DLGAP4 Polyclonal Antibody – Cat# MBS151064

Western blot analysis of SAPAP4 in SK-N-SH cell lysate with SAPAP4 antibody at 1 μg/mL.

DLGAP4 Antibody – Rabbit Polyclonal

Name: DLGAP4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS151064
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151064

SAPAP4 Antibody: SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SAPAP4 (DLGAP4), Polyclonal Antibody

Full Product Name

SAPAP4 Antibody

Product Gene Name

anti-DLGAP4 antibody

Product Synonym Names

SAPAP4; DAP4; DLP4; SAPAP4; DAP4; KIAA0964; Disks large-associated protein 4; DAP-4; discs, large (Drosophila) homolog-associated protein 4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

SAPAP4 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL (lot specific)

Specificity

At least three isoforms of SAPAP2 are known to exist. This SAPAP4 antibody will not cross-react with other SAPAP proteins.

Preparation and Storage

SAPAP4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antibody/Peptide Pairs

SAPAP4 peptide (MBS152153) is used for blocking the activity of SAPAP4 antibody (MBS151064)

Molecular Weight

49,478 Da

3D Structure

ModBase 3D Structure for Q9Y2H0

Conjugate

Unconjugated

Immunogen

SAPAP4 antibody was raised against a 13 amino acid synthetic peptide from near the center of human SAPAP4.

Buffer

SAPAP4 Antibody is supplied in PBS containing 0.02% sodium azide.

Applications Tested/Suitable for anti-DLGAP4 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-DLGAP4 antibody

SAPAP4 antibody can be used for detection of SAPAP4 by Western blot at 1 mug/mL.

Other Notes

Small volumes of anti-DLGAP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLGAP4 purchase

MBS151064 is an antibody targeting DLGAP4. Also known as SAPAP4 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DLGAP4. It may not necessarily be applicable to this product.

NCBI GI #

34335253

NCBI GeneID

22839

NCBI Accession #

NP_055717

UniProt Primary Accession #

Q9Y2H0

UniProt Secondary Accession #

Q5QPG4; Q5T2Y4; Q5T2Y5; Q9H137; Q9H138; Q9H1L7; E1P5T5

UniProt Related Accession #

Q9Y2H0

GenBank Nucleotide #

NM_014902.5

NCBI Official Full Name

disks large-associated protein 4 isoform a

NCBI Official Synonym Full Names

discs, large (Drosophila) homolog-associated protein 4

NCBI Official Symbol

DLGAP4

NCBI Official Synonym Symbols

DAP4; DLP4; DAP-4; SAPAP4; SAPAP-4

UniProt Protein Name

Disks large-associated protein 4

UniProt Synonym Protein Names

PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4; SAPAP-4

Protein Family

Disks large-associated protein

UniProt Gene Name

DLGAP4

UniProt Synonym Gene Names

DAP4; KIAA0964; SAPAP4; DAP-4; SAPAP-4

UniProt Entry Name

DLGP4_HUMAN

NCBI Protein Information

disks large-associated protein 4; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4

NCBI Summary for DLGAP4

The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for DLGAP4

SAPAP4: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, peripheral; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: membrane; synapse

Molecular Function: protein binding

Biological Process: cell-cell signaling

Research Articles on DLGAP4

1. Shows that an homologous rat protein can interact with nArgBP2, a novel neural member of the ponsin/ArgB/vinexin family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-DLGAP4 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1 publications with DLGAP4 and Blood
Lung Antibodies	>1 publications with DLGAP4 and Lung
Skin Antibodies	>1 publications with DLGAP4 and Skin
Brain Antibodies	>1 publications with DLGAP4 and Brain