• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CRMP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151082

CRMP1 Antibody: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRMP1, Polyclonal Antibody
Full Product Name
CRMP1 Antibody
Product Gene Name
anti-CRMP1 antibody
Product Synonym Names
CRMP1; DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3; ULIP3; Dihydropyrimidinase-related protein 1; Collapsin response mediator protein 1; collapsin response mediator protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
CRMP1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
CRMP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
CRMP1 peptide (MBS152057) is used for blocking the activity of CRMP1 antibody (MBS151082)
Molecular Weight
74,262 Da
OMIM
602462
3D Structure
ModBase 3D Structure for Q14194
Conjugate
Unconjugated
Immunogen
CRMP1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human CRMP1.
Buffer
CRMP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-CRMP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CRMP1 antibody
CRMP1 antibody can be used for the detection of CRMP1 by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2 mug/mL. For immunofluorescence start at 10 mug/mL.

Western Blot (WB) of anti-CRMP1 antibody

Western blot analysis of CRMP1 in human brain tissue lysate with CRMP1 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-CRMP1 Polyclonal Antibody – Cat# MBS151082

Immunohistochemistry (IHC) of anti-CRMP1 antibody

Immunohistochemistry of CRMP in human brain tissue with CRMP antibody at 2 μg/mL.
Rabbit Anti-CRMP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151082

Immunofluorescence (IF) of anti-CRMP1 antibody

Immunofluorescence of CRMP1 in Human Brain cells with CRMP1 antibody at 10 μg/mL.
Rabbit Anti-CRMP1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151082

Other Notes

Small volumes of anti-CRMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRMP1 purchase

MBS151082 is an antibody targeting CRMP1. Also known as CRMP1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CRMP1. It may not necessarily be applicable to this product.

NCBI GI #
14043246
NCBI GeneID
1400
NCBI Accession #
AAH07613
UniProt Primary Accession #
Q14194
UniProt Secondary Accession #
Q13024; Q4W5F1; Q96TC8; A0EJG6
UniProt Related Accession #
Q14194
NCBI Official Full Name
Collapsin response mediator protein 1
NCBI Official Synonym Full Names
collapsin response mediator protein 1
NCBI Official Symbol
CRMP1
NCBI Official Synonym Symbols
DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3
UniProt Protein Name
Dihydropyrimidinase-related protein 1
UniProt Synonym Protein Names
Collapsin response mediator protein 1; CRMP-1; Unc-33-like phosphoprotein 3; ULIP-3
Protein Family
Dihydropyrimidinase-related protein
UniProt Gene Name
CRMP1
UniProt Synonym Gene Names
DPYSL1; ULIP3; DRP-1; CRMP-1; ULIP-3
UniProt Entry Name
DPYL1_HUMAN
NCBI Protein Information
dihydropyrimidinase-related protein 1; dihydropyrimidinase-like 1; unc-33-like phosphoprotein 3

NCBI Summary for CRMP1

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CRMP1

CRMP-1: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Cell development/differentiation; Hydrolase

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cell soma; cytoplasm; dendrite; microtubule organizing center; spindle; cytosol

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; protein binding

Biological Process: axon guidance; nervous system development; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; pyrimidine base catabolic process
Show more

Research Articles on CRMP1

1. in pilocarpine-induced animal model of epilepsy, CRMP-1 dynamically decreased in a range of 2 months. Thus, our results indicate that CRMP-1 may be involved in the development of TLE

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CRMP1 antibody

 Reference Product  PubMed Publications
 SEMA3A antibody  >17 publications with CRMP1 and SEMA3A
 CDK5 antibody  >7 publications with CRMP1 and CDK5
 PLXNA1 antibody  >2 publications with CRMP1 and PLXNA1
 FYN antibody  >2 publications with CRMP1 and FYN
 CDK5R1 antibody  >1 publications with CRMP1 and CDK5R1
 PLXNA4 antibody  >1 publications with CRMP1 and PLXNA4
 PLXNA3 antibody  >1 publications with CRMP1 and PLXNA3
 DPYSL2 antibody  >1 publications with CRMP1 and DPYSL2

Pathways associated with anti-CRMP1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CRMPs In Sema3A Signaling Pathway antibodies  CRMPs In Sema3A Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with anti-CRMP1 antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >4 publications with CRMP1 and Neoplasm Metastasis
 Inflammation Antibodies  >3 publications with CRMP1 and Inflammation
 Disease Models, Animal Antibodies  >2 publications with CRMP1 and Disease Models, Animal
 Necrosis Antibodies  >2 publications with CRMP1 and Necrosis
 Movement Disorders Antibodies  >1 publications with CRMP1 and Movement Disorders
 Nerve Degeneration Antibodies  >1 publications with CRMP1 and Nerve Degeneration
 Congenital Abnormalities Antibodies  >1 publications with CRMP1 and Congenital Abnormalities
 Carcinoma, Hepatocellular Antibodies  >1 publications with CRMP1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CRMP1 and Liver Neoplasms
 Seizures Antibodies  >1 publications with CRMP1 and Seizures

Organs/Tissues associated with anti-CRMP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >51 publications with CRMP1 and Nerve
 Brain Antibodies  >24 publications with CRMP1 and Brain
 Lung Antibodies  >10 publications with CRMP1 and Lung
 Embryonic Tissue Antibodies  >8 publications with CRMP1 and Embryonic Tissue
 Muscle Antibodies  >6 publications with CRMP1 and Muscle
 Heart Antibodies  >1 publications with CRMP1 and Heart
 Intestine Antibodies  >1 publications with CRMP1 and Intestine
 Testis Antibodies  >1 publications with CRMP1 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with CRMP1 and Uncharacterized Tissue
 Eye Antibodies  >1 publications with CRMP1 and Eye
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000