Rabbit Anti-PPAPDC1B Polyclonal Antibody – Cat# MBS151119

Western blot analysis of PPAPDC1B in EL4 cell lysate with PPAPDC1B antibody at (A) 1 and (B) 2 μg/mL.

PPAPDC1B Antibody – Rabbit Polyclonal

Name: PPAPDC1B Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS151119
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151119

PPAPDC1B Antibody: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PPAPDC1B, Polyclonal Antibody

Full Product Name

PPAPDC1B Antibody

Product Gene Name

anti-PPAPDC1B antibody

Product Synonym Names

PPAPDC1B; DPPL1; HTPAP; DPPL1; Phosphatidate phosphatase PPAPDC1B; Phosphatidic acid phosphatase type 2 domain-containing protein 1B; phosphatidic acid phosphatase type 2 domain containing 1B

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Liquid

Purity/Purification

PPAPDC1B Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL (lot specific)

Preparation and Storage

PPAPDC1B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antibody/Peptide Pairs

PPAPDC1B peptide (MBS152968) is used for blocking the activity of PPAPDC1B antibody (MBS151119)

Molecular Weight

19,677 Da

OMIM

610626

3D Structure

ModBase 3D Structure for Q8NEB5

Conjugate

Unconjugated

Immunogen

PPAPDC1B antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human PPAPDC1B.

Buffer

PPAPDC1B Antibody is supplied in PBS containing 0.02% sodium azide.

Applications Tested/Suitable for anti-PPAPDC1B antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-PPAPDC1B antibody

PPAPDC1B antibody can be used for detection of PPAPDC1B by Western blot at 1 - 2 mug/mL.

Other Notes

Small volumes of anti-PPAPDC1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPAPDC1B purchase

MBS151119 is an antibody targeting PPAPDC1B. Also known as PPAPDC1B Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPAPDC1B. It may not necessarily be applicable to this product.

NCBI GI #

156523237

NCBI GeneID

84513

NCBI Accession #

NP_001096029

UniProt Primary Accession #

Q8NEB5

UniProt Secondary Accession #

Q3KQX6; Q9BY45; C9JKF5

UniProt Related Accession #

Q8NEB5

GenBank Nucleotide #

NM_001102559.1

NCBI Official Full Name

phosphatidate phosphatase PPAPDC1B isoform 1

NCBI Official Synonym Full Names

phosphatidic acid phosphatase type 2 domain containing 1B

NCBI Official Symbol

PPAPDC1B

NCBI Official Synonym Symbols

DPPL1; HTPAP

UniProt Protein Name

Phosphatidate phosphatase PPAPDC1B

UniProt Synonym Protein Names

Phosphatidic acid phosphatase type 2 domain-containing protein 1B

UniProt Gene Name

PPAPDC1B

UniProt Synonym Gene Names

DPPL1; HTPAP

UniProt Entry Name

PPC1B_HUMAN

NCBI Protein Information

phosphatidate phosphatase PPAPDC1B; diacylglycerol pyrophosphate like 1; phosphatidic acid phosphatase type 2 domain-containing protein 1B

UniProt Comments for PPAPDC1B

PPAPDC1B: Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma. Belongs to the PA-phosphatase related phosphoesterase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor; EC 3.1.3.4; Membrane protein, integral; Hydrolase; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8p11.23

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function: phosphatidate phosphatase activity

Biological Process: phospholipid dephosphorylation

Research Articles on PPAPDC1B

1. PPAPDC1B and WHSC1L1 played a major role in regulating the survival of breast cancer, pancreatic adenocarcinoma and small-cell lung cancer-derived cell lines.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPAPDC1B antibody

Reference Product	PubMed Publications
WHSC1L1 antibody	>2 publications with PPAPDC1B and WHSC1L1
BAG4 antibody	>1 publications with PPAPDC1B and BAG4
LSM1 antibody	>1 publications with PPAPDC1B and LSM1
DDHD2 antibody	>1 publications with PPAPDC1B and DDHD2

Pathways associated with anti-PPAPDC1B antibody

Products by Pathway	Pathway Diagram
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies	Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Role Of Phospholipids In Phagocytosis Pathway antibodies	Role Of Phospholipids In Phagocytosis Pathway Diagram

Organs/Tissues associated with anti-PPAPDC1B antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with PPAPDC1B and Kidney
Testis Antibodies	>1 publications with PPAPDC1B and Testis
Brain Antibodies	>1 publications with PPAPDC1B and Brain
Lung Antibodies	>1 publications with PPAPDC1B and Lung