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IRGC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151122

IRGC Antibody: Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
IRGC, Polyclonal Antibody
Full Product Name
IRGC Antibody
Product Gene Name
anti-IRGC antibody
Product Synonym Names
IRGC; IFGGE; IRGC1; Iigp5; CINEMA; R30953_1; IIGP5; Interferon-inducible GTPase 5; Immunity-related GTPase cinema 1; immunity-related GTPase family, cinema
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
IRGC Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
Two isoforms of IRGC are known to exist; this antibody will recognize both isoforms.
Preparation and Storage
IRGC antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
IRGC peptide (MBS152919) is used for blocking the activity of IRGC antibody (MBS151122)
Molecular Weight
50,288 Da
3D Structure
ModBase 3D Structure for Q6NXR0
Conjugate
Unconjugated
Immunogen
IRGC antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human IRGC.
Buffer
IRGC Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-IRGC antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-IRGC antibody
IRGC antibody can be used for detection of IRGC by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-IRGC antibody

Western blot analysis of IRGC in mouse brain tissue lysate with IRGC antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-IRGC Polyclonal Antibody – Cat# MBS151122

Immunocytochemistry (IHC) of anti-IRGC antibody

Immunocytochemistry of IRGC in A20 cells with IRGC antibody at 2.5 μg/mL.
Rabbit Anti-IRGC Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS151122

Immunofluorescence (IF) of anti-IRGC antibody

Immunofluorescence of IRGCb in A20 cells with IRGCb antibody at 20 μg/mL.
Rabbit Anti-IRGC Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151122

Other Notes

Small volumes of anti-IRGC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IRGC purchase

MBS151122 is an antibody targeting IRGC. Also known as IRGC Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IRGC. It may not necessarily be applicable to this product.

NCBI GI #
10257429
NCBI GeneID
56269
NCBI Accession #
NP_062558
UniProt Primary Accession #
Q6NXR0
UniProt Secondary Accession #
Q05BR8
UniProt Related Accession #
Q6NXR0
GenBank Nucleotide #
NM_019612.3
NCBI Official Full Name
interferon-inducible GTPase 5
NCBI Official Synonym Full Names
immunity-related GTPase family, cinema
NCBI Official Symbol
IRGC
NCBI Official Synonym Symbols
IFGGE; IRGC1; Iigp5; CINEMA; R30953_1
UniProt Protein Name
Interferon-inducible GTPase 5
UniProt Synonym Protein Names
Immunity-related GTPase cinema 1
Protein Family
Interferon-inducible GTPase
UniProt Gene Name
IRGC
UniProt Synonym Gene Names
IIGP5; IRGC1
UniProt Entry Name
IIGP5_HUMAN
NCBI Protein Information
interferon-inducible GTPase 5; interferon inducible GTPase 5; immunity-related GTPase cinema 1; immunity-related GTPase family, cinema 1; interferon-gamma-inducible GTPase IFGGE protein

UniProt Comments for IRGC

IRGC: Belongs to the interferon-inducible GTPase family.

Protein type: EC 3.6.5.-; Hydrolase

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: membrane

Molecular Function: GTP binding; hydrolase activity

Biological Process: metabolic process

Research Articles on IRGC

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IRGC antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with IRGC and Brain
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