• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ZIMP10 (ZMIZ1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151128

ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZIMP10 (ZMIZ1), Polyclonal Antibody
Full Product Name
ZIMP10 Antibody
Product Gene Name
Product Synonym Names
ZIMP10; MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10; KIAA1224; Zinc finger MIZ domain-containing protein 1; PIAS-like protein Zimp10; zinc finger, MIZ-type containing 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
ZIMP10 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least three isoforms are known to exist; this antibody will recognize all three. ZIMP10 antibody is predicted to not cross-react with other PIAS protein family members.
Preparation and Storage
ZIMP10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZIMP10 peptide (MBS153212) is used for blocking the activity of ZIMP10 antibody (MBS151128)
Molecular Weight
107,270 Da
OMIM
607159
3D Structure
ModBase 3D Structure for Q9ULJ6
Conjugate
Unconjugated
Immunogen
ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10.
Buffer
ZIMP10 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ZMIZ1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-ZMIZ1 antibody
ZIMP10 antibody can be used for detection of ZIMP10 by Western blot at 0.5 mug/mL. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ZMIZ1 antibody

Western blot analysis of ZIMP10 in K562 cell lysate with ZIMP10 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide
Rabbit Anti-ZMIZ1 Polyclonal Antibody – Cat# MBS151128

Immunocytochemistry (IHC) of anti-ZMIZ1 antibody

Immunocytochemistry of ZIMP10 in K562 cells with ZIMP10 antibody at 10 μg/mL.
Rabbit Anti-ZMIZ1 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS151128

Immunofluorescence (IF) of anti-ZMIZ1 antibody

Immunofluorescence of ZIMP10 in K562 cells with ZIMP10 antibody at 20 μg/mL.
Rabbit Anti-ZMIZ1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151128

Other Notes

Small volumes of anti-ZMIZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZMIZ1 purchase

MBS151128 is an antibody targeting ZMIZ1. Also known as ZIMP10 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZMIZ1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger MIZ domain-containing protein 1
NCBI Official Synonym Full Names
zinc finger, MIZ-type containing 1
NCBI Official Symbol
ZMIZ1
NCBI Official Synonym Symbols
MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10
UniProt Protein Name
Zinc finger MIZ domain-containing protein 1
UniProt Synonym Protein Names
PIAS-like protein Zimp10; Retinoic acid-induced protein 17
UniProt Gene Name
ZMIZ1
UniProt Synonym Gene Names
KIAA1224; RAI17; ZIMP10
UniProt Entry Name
ZMIZ1_HUMAN
NCBI Protein Information
zinc finger MIZ domain-containing protein 1; RP11-519K18.1; FLJ00092 protein; retinoic acid induced 17; zinc finger-containing, Miz1, PIAS-like protein on chromosome 10

NCBI Summary for ZMIZ1

This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Show more

UniProt Comments for ZMIZ1

RAI17: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 10q22.3

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; nuclear speck

Molecular Function: zinc ion binding

Biological Process: heart morphogenesis; developmental growth; positive regulation of fibroblast proliferation; transcription, DNA-dependent; in utero embryonic development; vitellogenesis; artery morphogenesis; cell aging; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZMIZ1 antibody

 Reference Product  PubMed Publications
 SMAD4 antibody  >1 publications with ZMIZ1 and SMAD4
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000