• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RGS22 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151166

RGS22 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit.… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RGS22, Polyclonal Antibody
Full Product Name
RGS22 Antibody
Product Gene Name
anti-RGS22 antibody
Product Synonym Names
RGS22; CT145; PRTD-NY2; Regulator of G-protein signaling 22; RGS22; regulator of G-protein signaling 22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
RGS22 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least four isoforms of RGS22 are known to exist; this antibody will detect the three longest isoforms. RGS22 antibody is predicted to not cross-react with other RGS proteins
Preparation and Storage
RGS22 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
RGS22 peptide (MBS152654) is used for blocking the activity of RGS22 antibody (MBS151166)
Molecular Weight
139 kDa
OMIM
615650
3D Structure
ModBase 3D Structure for Q8NE09
Conjugate
Unconjugated
Immunogen
RGS22 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human RGS22.
Buffer
RGS22 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-RGS22 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-RGS22 antibody
RGS22 antibody can be used for detection of RGS22 by Western blot at 1 - 2 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-RGS22 antibody

Western blot analysis of RGS22 in Jurkat cell lysate with RGS22 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-RGS22 Polyclonal Antibody – Cat# MBS151166

Immunofluorescence (IF) of anti-RGS22 antibody

Immunofluorescence of RGS22 in human testis tissue with RGS22 antibody at 20 μg/mL.
Rabbit Anti-RGS22 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151166

Other Notes

Small volumes of anti-RGS22 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RGS22 purchase

MBS151166 is an antibody targeting RGS22. Also known as RGS22 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS22. It may not necessarily be applicable to this product.

NCBI GI #
158534077
NCBI GeneID
26166
NCBI Accession #
NP_056483
UniProt Primary Accession #
Q8NE09
UniProt Secondary Accession #
Q569L2; Q86Y71; Q9BYZ4; Q9UFN6; A8K944
UniProt Related Accession #
Q8NE09
GenBank Nucleotide #
NM_015668.4
NCBI Official Full Name
regulator of G-protein signaling 22 isoform 1
NCBI Official Synonym Full Names
regulator of G-protein signaling 22
NCBI Official Symbol
RGS22
NCBI Official Synonym Symbols
CT145; PRTD-NY2
UniProt Protein Name
Regulator of G-protein signaling 22
Protein Family
Regulator of G-protein signaling
UniProt Gene Name
RGS22
UniProt Synonym Gene Names
RGS22
UniProt Entry Name
RGS22_HUMAN
NCBI Protein Information
regulator of G-protein signaling 22

UniProt Comments for RGS22

RGS22: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, RGS; GAPs; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: GTPase activator activity

Biological Process: positive regulation of GTPase activity
Show more

Research Articles on RGS22

1. New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22(rs7006527).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RGS22 antibody

 Reference Product  PubMed Publications
 GNA11 antibody  >1 publications with RGS22 and GNA11
 GNA13 antibody  >1 publications with RGS22 and GNA13

Diseases associated with anti-RGS22 antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >1 publications with RGS22 and Neoplasm Metastasis

Organs/Tissues associated with anti-RGS22 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with RGS22 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000