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SYNGR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151196

SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic… More details

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Product Overview

Online Datasheet in PDF
Product Name
SYNGR1, Polyclonal Antibody
Full Product Name
SYNGR1 Antibody
Product Gene Name
Product Synonym Names
SYNGR1; Synaptogyrin-1; synaptogyrin 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
SYNGR1 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SYNGR1 peptide (MBS152203) is used for blocking the activity of SYNGR1 antibody (MBS151196)
Molecular Weight
21,591 Da
OMIM
603925
3D Structure
ModBase 3D Structure for O43759
Conjugate
Unconjugated
Immunogen
SYNGR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SYNGR1.
Buffer
SYNGR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SYNGR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SYNGR1 antibody
SYNGR1 antibody can be used for detection of SYNGR1 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SYNGR1 antibody

Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-SYNGR1 Polyclonal Antibody – Cat# MBS151196

Immunohistochemistry (IHC) of anti-SYNGR1 antibody

Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 μg/mL.
Rabbit Anti-SYNGR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151196

Immunofluorescence (IF) of anti-SYNGR1 antibody

Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 μg/mL.
Rabbit Anti-SYNGR1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151196

Other Notes

Small volumes of anti-SYNGR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYNGR1 purchase

MBS151196 is an antibody targeting SYNGR1. Also known as SYNGR1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYNGR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
synaptogyrin 1a
NCBI Official Synonym Full Names
synaptogyrin 1
NCBI Official Symbol
SYNGR1
UniProt Protein Name
Synaptogyrin-1
Protein Family
UniProt Gene Name
SYNGR1
UniProt Entry Name
SNG1_HUMAN
NCBI Protein Information
synaptogyrin-1

NCBI Summary for SYNGR1

This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for SYNGR1

SYNGR1: Involved in the regulation of short-term and long-term synaptic plasticity. Belongs to the synaptogyrin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: synaptic vesicle membrane; melanosome; integral to membrane; neuromuscular junction; cell junction

Biological Process: regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; protein targeting
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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