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PTCHD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151200

PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored… More details

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Product Overview

Online Datasheet in PDF
Product Name
PTCHD2, Polyclonal Antibody
Full Product Name
PTCHD2 Antibody
Product Gene Name
Product Synonym Names
PTCHD2; DISP3; DISP3; KIAA1337; Patched domain-containing protein 2; Protein dispatched homolog 3; patched domain containing 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
PTCHD2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of PTCHD2 are known to exist. This antibody is specific for PTCHD2 and will not recognize the other DISP family of proteins.
Preparation and Storage
PTCHD2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
PTCHD2 peptide (MBS152018) is used for blocking the activity of PTCHD2 antibody (MBS151200)
Molecular Weight
103,766 Da
OMIM
611251
3D Structure
ModBase 3D Structure for Q9P2K9
Conjugate
Unconjugated
Immunogen
PTCHD2 antibody was raised against a 19 amino acid synthetic peptide from near the center of human PTCHD2.
Buffer
PTCHD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-PTCHD2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-PTCHD2 antibody
PTCHD2 antibody can be used for detection of EPAC1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-PTCHD2 antibody

Western blot analysis of PTCHD2 in mouse kidney tissue lysate with PTCHD2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-PTCHD2 Polyclonal Antibody – Cat# MBS151200

Immunohistochemistry (IHC) of anti-PTCHD2 antibody

Immunohistochemistry of PTCHD2 in human kidney tissue with PTCHD2 antibody at 2.5 μg/mL.
Rabbit Anti-PTCHD2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151200

Immunofluorescence (IF) of anti-PTCHD2 antibody

Immunofluorescence of PTCHD2 in human kidney tissue with PTCHD2 antibody at 20 μg/mL.
Rabbit Anti-PTCHD2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151200

Other Notes

Small volumes of anti-PTCHD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTCHD2 purchase

MBS151200 is an antibody targeting PTCHD2. Also known as PTCHD2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTCHD2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
patched domain-containing protein 2
NCBI Official Synonym Full Names
patched domain containing 2
NCBI Official Symbol
PTCHD2
NCBI Official Synonym Symbols
DISP3
UniProt Protein Name
Patched domain-containing protein 2
UniProt Synonym Protein Names
Protein dispatched homolog 3
UniProt Gene Name
PTCHD2
UniProt Synonym Gene Names
DISP3; KIAA1337
UniProt Entry Name
PTHD2_HUMAN
NCBI Protein Information
patched domain-containing protein 2; dispatched 3; protein dispatched homolog 3

UniProt Comments for PTCHD2

PTCHD2: Belongs to the patched family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: nuclear membrane; endoplasmic reticulum; integral to membrane

Molecular Function: hedgehog receptor activity

Biological Process: cholesterol homeostasis; smoothened signaling pathway; regulation of lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTCHD2 antibody

 Reference Product  PubMed Publications
 DISP1 antibody  >1 publications with PTCHD2 and DISP1

Diseases associated with anti-PTCHD2 antibody

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