• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RANBP10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151209

RANBP10 Antibody: The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RANBP10, Polyclonal Antibody
Full Product Name
RANBP10 Antibody
Product Gene Name
anti-RANBP10 antibody
Product Synonym Names
RANBP10; KIAA1464; Ran-binding protein 10; RanBP10; RAN binding protein 10
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
RANBP10 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
RANBP10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
RANBP10 peptide (MBS153270) is used for blocking the activity of RANBP10 antibody (MBS151209)
Molecular Weight
64,542 Da
OMIM
614031
3D Structure
ModBase 3D Structure for Q6VN20
Conjugate
Unconjugated
Immunogen
RANBP10 antibody was raised against a 15 amino acid synthetic peptide near the center of human RANBP10.
Buffer
RANBP10 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-RANBP10 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-RANBP10 antibody
RANBP10 antibody can be used for detection of RANBP10 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-RANBP10 antibody

Western blot analysis of RANBP10 in human skeletal muscle tissue lysate with RANBP10 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-RANBP10 Polyclonal Antibody – Cat# MBS151209

Immunohistochemistry (IHC) of anti-RANBP10 antibody

Immunohistochemistry of RANBP10 in human skeletal muscle tissue with RANBP10 antibody at 5 μg/mL.
Rabbit Anti-RANBP10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151209

Immunofluorescence (IF) of anti-RANBP10 antibody

Immunofluorescence of RANBP10 in mouse skeletal muscle tissue with RANBP10 antibody at 20 μg/mL.
Rabbit Anti-RANBP10 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151209

Other Notes

Small volumes of anti-RANBP10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RANBP10 purchase

MBS151209 is an antibody targeting RANBP10. Also known as RANBP10 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RANBP10. It may not necessarily be applicable to this product.

NCBI GI #
119603573
NCBI GeneID
57610
NCBI Accession #
EAW83167
UniProt Primary Accession #
Q6VN20
UniProt Secondary Accession #
Q9P264; A4FTY2; B4DID0; B4DQH9; E7EW27
UniProt Related Accession #
Q6VN20
NCBI Official Full Name
RAN binding protein 10, isoform CRA_a
NCBI Official Synonym Full Names
RAN binding protein 10
NCBI Official Symbol
RANBP10
UniProt Protein Name
Ran-binding protein 10
Protein Family
Ran-binding protein
UniProt Gene Name
RANBP10
UniProt Synonym Gene Names
KIAA1464; RanBP10
UniProt Entry Name
RBP10_HUMAN
NCBI Protein Information
ran-binding protein 10

UniProt Comments for RANBP10

RANBP10: Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway. Belongs to the RANBP9/10 family.

Protein type: GEFs; GEFs, Ras; GAPs; GAPs, Ras

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasmic microtubule; cytosol; nucleus

Molecular Function: Ran guanyl-nucleotide exchange factor activity; beta-tubulin binding; Ran GTPase binding

Biological Process: microtubule cytoskeleton organization and biogenesis
Show more

Research Articles on RANBP10

1. data support the idea that RanBP9 and RanBP10 may function as signaling integrators and dictate the efficient regulation of D(1) receptor signaling by PKCdelta and PKCgamma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RANBP10 antibody

 Reference Product  PubMed Publications
 RANBP9 antibody  >4 publications with RANBP10 and RANBP9
 MET antibody  >2 publications with RANBP10 and MET

Pathways associated with anti-RANBP10 antibody

 Products by Pathway  Pathway Diagram
 Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway antibodies  Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway Diagram

Diseases associated with anti-RANBP10 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with RANBP10 and Immune System Diseases

Organs/Tissues associated with anti-RANBP10 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with RANBP10 and Nerve
 Liver Antibodies  >1 publications with RANBP10 and Liver
 Kidney Antibodies  >1 publications with RANBP10 and Kidney
 Prostate Antibodies  >1 publications with RANBP10 and Prostate
 Embryonic Tissue Antibodies  >1 publications with RANBP10 and Embryonic Tissue
 Uterus Antibodies  >1 publications with RANBP10 and Uterus
 Brain Antibodies  >1 publications with RANBP10 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000