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SLITRK6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151265

Slitrk6 Antibody: SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Slitrk6, Polyclonal Antibody
Full Product Name
Slitrk6 Antibody
Product Gene Name
anti-SLITRK6 antibody
Product Synonym Names
Slitrk6; DFNMYP; SLIT and NTRK-like protein 6; SLIT and NTRK-like family, member 6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid;Slitrk6 Antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
Slitrk6 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Preparation and Storage
Slitrk6 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Slitrk6 peptide (MBS152256) is used for blocking the activity of Slitrk6 antibody (MBS151265)
OMIM
phenotype 609681
3D Structure
ModBase 3D Structure for Q9H5Y7
Conjugate
Unconjugated
Immunogen
Slitrk6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human Slitrk6.
The immunogen is located within amino acids 250-300 of Slitrk6
Applications Tested/Suitable for anti-SLITRK6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
Application Notes for anti-SLITRK6 antibody
Optimal dilutions for each application to be determined by the researcher

Western Blot (WB) of anti-SLITRK6 antibody

Western blot analysis of Slitrk6 in mouse lung tissue lysate with Slitrk6 antibody at (A) 0.5 and (B) 1 μg/mL.
Rabbit Anti-SLITRK6 Polyclonal Antibody – Cat# MBS151265

Immunohistochemistry (IHC) of anti-SLITRK6 antibody

Immunohistochemistry of Slitrk6 in human brain tissue with Slitrk6 antibody at 2.5 μg/mL.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151265

Immunofluorescence (IF) of anti-SLITRK6 antibody

Immunofluorescence of Slitrk6 in Human Brain cells with Slitrk6 antibody at 20 μg/mL.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151265

Other Notes

Small volumes of anti-SLITRK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLITRK6 purchase

MBS151265 is an antibody targeting SLITRK6. Also known as Slitrk6 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLITRK6. It may not necessarily be applicable to this product.

NCBI GI #
59803110
NCBI GeneID
84189
NCBI Accession #
Q9H5Y7.3
UniProt Primary Accession #
Q9H5Y7
UniProt Secondary Accession #
Q495Q0; Q6AW93; Q9HAA8; Q9NT60; A8K9S8
UniProt Related Accession #
Q9H5Y7
NCBI Official Full Name
SLIT and NTRK-like protein 6
NCBI Official Synonym Full Names
SLIT and NTRK-like family, member 6
NCBI Official Symbol
SLITRK6
NCBI Official Synonym Symbols
DFNMYP
UniProt Protein Name
SLIT and NTRK-like protein 6
Protein Family
SLIT and NTRK-like protein
UniProt Gene Name
SLITRK6
UniProt Entry Name
SLIK6_HUMAN
NCBI Protein Information
SLIT and NTRK-like protein 6; 4832410J21Rik; slit and trk like gene 6

NCBI Summary for SLITRK6

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]
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UniProt Comments for SLITRK6

SLITRK6: Suppresses neurite outgrowth. Belongs to the SLITRK family.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: cell surface; integral to plasma membrane

Biological Process: vestibulocochlear nerve development; lens development in camera-type eye; startle response; synaptogenesis; sensory perception of sound; axonogenesis; visual perception; adult locomotory behavior; multicellular organism growth; auditory receptor cell morphogenesis; auditory behavior; linear vestibuloocular reflex

Disease: Deafness And Myopia
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Research Articles on SLITRK6

1. SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLITRK6 antibody

 Reference Product  PubMed Publications
 NTRK1 antibody  >2 publications with SLITRK6 and NTRK1
 BDNF antibody  >1 publications with SLITRK6 and BDNF

Diseases associated with anti-SLITRK6 antibody

 Disease Name  Pubmed Publications
 Memory Disorders Antibodies  >1 publications with SLITRK6 and Memory Disorders
 Fetal Death Antibodies  >1 publications with SLITRK6 and Fetal Death
 Learning Disorders Antibodies  >1 publications with SLITRK6 and Learning Disorders

Organs/Tissues associated with anti-SLITRK6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with SLITRK6 and Brain
 Eye Antibodies  >3 publications with SLITRK6 and Eye
 Embryonic Tissue Antibodies  >2 publications with SLITRK6 and Embryonic Tissue
 Bone Antibodies  >1 publications with SLITRK6 and Bone
 Muscle Antibodies  >1 publications with SLITRK6 and Muscle
 Lung Antibodies  >1 publications with SLITRK6 and Lung
 Pancreas Antibodies  >1 publications with SLITRK6 and Pancreas
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