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ATP11A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151310

ATP11A Antibody: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A… More details

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Product Overview

Online Datasheet in PDF
Product Name
ATP11A, Polyclonal Antibody
Full Product Name
ATP11A Antibody
Product Gene Name
anti-ATP11A antibody
Product Synonym Names
ATP11A; ATPIH; ATPIS; ATPIH; KIAA1021; Probable phospholipid-transporting ATPase IH; ATPase IS; ATPase, class VI, type 11A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
ATP11A Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
ATP11A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ATP11A peptide (MBS152380) is used for blocking the activity of ATP11A antibody (MBS151310)
Molecular Weight
129,756 Da
OMIM
605868
3D Structure
ModBase 3D Structure for P98196
Conjugate
Unconjugated
Immunogen
ATP11A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A.
Buffer
ATP11A Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ATP11A antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-ATP11A antibody
ATP11A antibody can be used for detection of ATP11A by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ATP11A antibody

Western blot analysis of ATP11A in K562 cell tissue lysate with ATP11A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-ATP11A Polyclonal Antibody – Cat# MBS151310

Immunocytochemistry (IHC) of anti-ATP11A antibody

Immunocytochemistry of ATP11A in K562 cells with ATP11A antibody at 10 μg/mL.
Rabbit Anti-ATP11A Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS151310

Immunofluorescence (IF) of anti-ATP11A antibody

Immunofluorescence of ATP11A in K562 cells with ATP11A antibody at 20 μg/mL.
Rabbit Anti-ATP11A Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151310

Other Notes

Small volumes of anti-ATP11A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP11A purchase

MBS151310 is an antibody targeting ATP11A. Also known as ATP11A Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP11A. It may not necessarily be applicable to this product.

NCBI GI #
150421681
NCBI GeneID
23250
NCBI Accession #
NP_115565
UniProt Primary Accession #
P98196
UniProt Secondary Accession #
Q5VXT2
UniProt Related Accession #
P98196
GenBank Nucleotide #
NM_032189.3
NCBI Official Full Name
probable phospholipid-transporting ATPase IH isoform b
NCBI Official Synonym Full Names
ATPase, class VI, type 11A
NCBI Official Symbol
ATP11A
NCBI Official Synonym Symbols
ATPIH; ATPIS
UniProt Protein Name
Probable phospholipid-transporting ATPase IH
UniProt Synonym Protein Names
ATPase IS; ATPase class VI type 11A; P4-ATPase flippase complex alpha subunit ATP11A
Protein Family
Probable phospholipid-transporting ATPase
UniProt Gene Name
ATP11A
UniProt Synonym Gene Names
ATPIH; ATPIS; KIAA1021
UniProt Entry Name
AT11A_HUMAN
NCBI Protein Information
probable phospholipid-transporting ATPase IH; phospholipid-translocating ATPase; potential phospholipid-transporting ATPase IH; P4-ATPase flippase complex alpha subunit ATP11A

NCBI Summary for ATP11A

The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for ATP11A

ATP11A: is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Hydrolase; EC 3.6.3.1; Transporter, ion channel; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: recycling endosome; membrane; intracellular membrane-bound organelle; lysosomal membrane; endoplasmic reticulum; early endosome; plasma membrane; integral to membrane

Molecular Function: phospholipid-translocating ATPase activity; protein binding; magnesium ion binding; ATP binding

Biological Process: phospholipid translocation; metabolic process
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Research Articles on ATP11A

1. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ATP11A antibody

 Products by Pathway  Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ion Transport By P-type ATPases Pathway antibodies  Ion Transport By P-type ATPases Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-ATP11A antibody

 Disease Name  Pubmed Publications
 Hyperglycemia Antibodies  >1 publications with ATP11A and Hyperglycemia
 Cholestasis Antibodies  >1 publications with ATP11A and Cholestasis
 Fibrosis Antibodies  >1 publications with ATP11A and Fibrosis
 Lung Diseases Antibodies  >1 publications with ATP11A and Lung Diseases
 Idiopathic Pulmonary Fibrosis Antibodies  >1 publications with ATP11A and Idiopathic Pulmonary Fibrosis

Organs/Tissues associated with anti-ATP11A antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with ATP11A and Blood
 Liver Antibodies  >1 publications with ATP11A and Liver
 Lung Antibodies  >1 publications with ATP11A and Lung
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