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H1N1 Neuraminidase (NA) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151366

H1N1 Neuraminidase Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
H1N1 Neuraminidase (NA), Polyclonal Antibody
Full Product Name
H1N1 Neuraminidase Antibody
Product Gene Name
Product Synonym Names
H1N1 Neuraminidase; neuraminidase / neuraminidase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Virus
Form/Format
Liquid
Purity/Purification
H1N1 Neuraminidase Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody will recognize the Neuraminidase from the both the seasonal influenza (H1N1) and swine-origin influenza virus (A/California/14/2009 (H1N1)).
Preparation and Storage
H1N1 Neuraminidase antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Molecular Weight
51,665 Da
3D Structure
ModBase 3D Structure for B1AGS8
Conjugate
Unconjugated
Immunogen
Neuraminidase antibody was raised against synthetic peptides from. The seasonal influenza (H1N1) Neuraminidase protein and the novel swine influenza Neuraminidase protein.

The antibody recognizes both variants.
Buffer
H1N1 Neuraminidase Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-NA antibody
ELISA (EIA)
Application Notes for anti-NA antibody
Neuraminidase antibody can be used for the detection of the Neuraminidase protein from the seasonal influenza A (H1N1) and the novel swine influenza in ELISA. It will detect 2 ng of free peptide at 1 mug/mL.

ELISA (EIA) of anti-NA antibody

ELISA results using H1N1 Neuraminidase antibody at 1 μg/mL and the blocking and corresponding peptides at 50, 10, 2 and 0 ng/mL.
Rabbit Anti-NA Polyclonal Antibody – Cat# MBS151366

Other Notes

Small volumes of anti-NA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NA purchase

MBS151366 is an antibody targeting NA. Also known as H1N1 Neuraminidase Antibody. Reactive in Virus. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
neuraminidase
UniProt Protein Name
Neuraminidase
Protein Family
UniProt Gene Name
NA
UniProt Entry Name
B1AGS8_9INFA

UniProt Comments for NA

Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moities on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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