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SLC39A2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151383

ZIP2 Antibody: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
ZIP2 (SLC39A2), Polyclonal Antibody
Full Product Name
ZIP2 Antibody
Product Gene Name
Product Synonym Names
ZIP2; 6A1; ZIP2; ETI-1; ZIP-2; Zinc transporter ZIP2; 6A1; solute carrier family 39 (zinc transporter), member 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
ZIP2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
ZIP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZIP2 peptide (MBS152142) is used for blocking the activity of ZIP2 antibody (MBS151383)
OMIM
612166
3D Structure
ModBase 3D Structure for Q9NP94
Conjugate
Unconjugated
Immunogen
ZIP2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZIP2.
The immunogen is located within amino acids 70-120 of ZIP2
Buffer
ZIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Molecular Weight
Predicted: 34kDa
Observed: 32kDa
Applications Tested/Suitable for anti-SLC39A2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SLC39A2 antibody
ZIP2 antibody can be used for detection of ZIP2 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SLC39A2 antibody

Western blot analysis of ZIP2 in (A) mouse and (B) rat brain tissue lysate with ZIP2 antibody at 1 μg/mL.
Rabbit Anti-SLC39A2 Polyclonal Antibody – Cat# MBS151383

Immunohistochemistry (IHC) of anti-SLC39A2 antibody

Immunohistochemistry of ZIP2 in human brain tissue with ZIP2 antibody at 2.5 μg/mL.
Rabbit Anti-SLC39A2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151383

Immunofluorescence (IF) of anti-SLC39A2 antibody

Immunofluorescence of ZIP2 in human brain tissue with ZIP2 antibody at 20 μg/mL.
Rabbit Anti-SLC39A2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151383

Other Notes

Small volumes of anti-SLC39A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A2 purchase

MBS151383 is an antibody targeting SLC39A2. Also known as ZIP2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP2 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 2
NCBI Official Symbol
SLC39A2
NCBI Official Synonym Symbols
6A1; ZIP2; ETI-1; ZIP-2
UniProt Protein Name
Zinc transporter ZIP2
UniProt Synonym Protein Names
6A1; Eti-1; Solute carrier family 39 member 2; Zrt- and Irt-like protein 2; ZIP-2; hZIP2
Protein Family
UniProt Gene Name
SLC39A2
UniProt Synonym Gene Names
ZIP2; ZIP-2; hZIP2
UniProt Entry Name
S39A2_HUMAN
NCBI Protein Information
zinc transporter ZIP2; zinc uptake transporter 2; Zrt- and Irt-like protein 2; solute carrier family 39 member 2

NCBI Summary for SLC39A2

This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010]

UniProt Comments for SLC39A2

SLC39A2: Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis. Belongs to the ZIP transporter (TC 2.A.5) family.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: integral to plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: zinc ion transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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