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C13ORF34 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151472

Bora Antibody: Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Bora (C13orf34), Polyclonal Antibody
Full Product Name
Bora Antibody
Product Gene Name
anti-C13orf34 antibody
Product Synonym Names
Bora; C13orf34; C13orf34; Protein aurora borealis; HsBora; chromosome 13 open reading frame 34
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Bora Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Bora antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Bora peptide (MBS152144) is used for blocking the activity of Bora antibody (MBS151472)
Molecular Weight
53,438 Da
OMIM
610510
3D Structure
ModBase 3D Structure for Q6PGQ7
Conjugate
Unconjugated
Immunogen
Bora antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human Bora.
Buffer
Bora Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-C13orf34 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-C13orf34 antibody
Bora antibody can be used for detection of Bora by Western blot at 1-2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-C13orf34 antibody

Western blot analysis of Bora in Jurkat cell lysate with Bora antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-C13ORF34 Polyclonal Antibody – Cat# MBS151472

Immunohistochemistry (IHC) of anti-C13orf34 antibody

Immunohistochemistry of Bora in mouse brain tissue with Bora antibody at 2.5 μg/mL.
Rabbit Anti-C13ORF34 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151472

Immunofluorescence (IF) of anti-C13orf34 antibody

Immunofluorescence of Bora in Mouse Brain cells with Bora antibody at 20 μg/mL.
Rabbit Anti-C13ORF34 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151472

Other Notes

Small volumes of anti-C13orf34 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C13orf34 purchase

MBS151472 is an antibody targeting C13orf34. Also known as Bora Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C13orf34. It may not necessarily be applicable to this product.

NCBI GI #
74737659
NCBI GeneID
79866
NCBI Accession #
Q6PGQ7.2
UniProt Primary Accession #
Q6PGQ7
UniProt Secondary Accession #
Q5W0P3; Q5W0P4; Q86YC6; Q96IW9; Q9H640; B4DQ30
UniProt Related Accession #
Q6PGQ7
NCBI Official Full Name
Protein aurora borealis
NCBI Official Synonym Full Names
bora, aurora kinase A activator
NCBI Official Symbol
BORA
NCBI Official Synonym Symbols
C13orf34
UniProt Protein Name
Protein aurora borealis
UniProt Gene Name
BORA
UniProt Synonym Gene Names
C13orf34; HsBora
UniProt Entry Name
BORA_HUMAN
NCBI Protein Information
protein aurora borealis

NCBI Summary for C13orf34

BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008]

UniProt Comments for C13orf34

BORA: Required for the activation of AURKA at the onset of mitosis. Interacts with AURKA. Belongs to the BORA family.

Protein type: Activator

Chromosomal Location of Human Ortholog: 13q22.1

Cellular Component: cytosol

Molecular Function: protein binding; protein kinase binding

Biological Process: mitosis; regulation of protein localization; cell division; regulation of mitosis; mitotic cell cycle; G2/M transition of mitotic cell cycle
Show more

Research Articles on C13orf34

1. Activation of Plk1 by Aurora-A may function as a bistable switch

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-C13orf34 antibody

 Reference Product  PubMed Publications
 PLK1 antibody  >15 publications with C13orf34 and PLK1
 AURKA antibody  >7 publications with C13orf34 and AURKA
 CDK1 antibody  >2 publications with C13orf34 and CDK1
 TTK antibody  >1 publications with C13orf34 and TTK
 BTRC antibody  >1 publications with C13orf34 and BTRC

Pathways associated with anti-C13orf34 antibody

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
 PLK1 Signaling Events Pathway antibodies  PLK1 Signaling Events Pathway Diagram
 Regulation Of PLK1 Activity At G2/M Transition Pathway antibodies  Regulation Of PLK1 Activity At G2/M Transition Pathway Diagram

Diseases associated with anti-C13orf34 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >61 publications with C13orf34 and Brain Diseases
 Inflammation Antibodies  >38 publications with C13orf34 and Inflammation
 Necrosis Antibodies  >26 publications with C13orf34 and Necrosis
 Fever Antibodies  >25 publications with C13orf34 and Fever
 Liver Diseases Antibodies  >24 publications with C13orf34 and Liver Diseases
 Kidney Diseases Antibodies  >23 publications with C13orf34 and Kidney Diseases
 Fibrosis Antibodies  >18 publications with C13orf34 and Fibrosis
 Breast Neoplasms Antibodies  >13 publications with C13orf34 and Breast Neoplasms
 Fatty Liver Antibodies  >12 publications with C13orf34 and Fatty Liver
 Hematologic Diseases Antibodies  >10 publications with C13orf34 and Hematologic Diseases

Organs/Tissues associated with anti-C13orf34 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >219 publications with C13orf34 and Blood
 Brain Antibodies  >110 publications with C13orf34 and Brain
 Eye Antibodies  >71 publications with C13orf34 and Eye
 Muscle Antibodies  >69 publications with C13orf34 and Muscle
 Bone Antibodies  >62 publications with C13orf34 and Bone
 Skin Antibodies  >61 publications with C13orf34 and Skin
 Kidney Antibodies  >60 publications with C13orf34 and Kidney
 Vascular Antibodies  >57 publications with C13orf34 and Vascular
 Liver Antibodies  >57 publications with C13orf34 and Liver
 Lung Antibodies  >34 publications with C13orf34 and Lung
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