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ZBED3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151505

ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently… More details

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Product Overview

Product Name
ZBED3, Polyclonal Antibody
Full Product Name
ZBED3 Antibody
Product Gene Name
Product Synonym Names
ZBED3; Zinc finger BED domain-containing protein 3; Axin-interacting protein; zinc finger, BED-type containing 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
ZBED3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
Preparation and Storage
ZBED3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZBED3 peptide (MBS152836) is used for blocking the activity of ZBED3 antibody (MBS151505)
Molecular Weight
25,132 Da
OMIM
615250
3D Structure
ModBase 3D Structure for Q96IU2
Conjugate
Unconjugated
Immunogen
ZBED3 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ZBED3.
Buffer
ZBED3 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ZBED3 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-ZBED3 antibody
ZBED3 antibody can be used for detection of ZBED3 by Western blot at 1 mug/mL. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. Antibody can also be used for immunocytochemistry starting at 20 mug/mL.

Western Blot (WB) of anti-ZBED3 antibody

Western blot analysis of ZBED3 in Jurkat cell lysate with ZBED3 antibody at 1 μg/ml.
Rabbit Anti-ZBED3 Polyclonal Antibody – Cat# MBS151505

Immunocytochemistry (IHC) of anti-ZBED3 antibody

Immunocytochemistry of ZBED3 in A549 cells with ZBED3 antibody at 20 μg/mL.
Rabbit Anti-ZBED3 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS151505

Other Notes

Small volumes of anti-ZBED3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZBED3 purchase

MBS151505 is an antibody targeting ZBED3. Also known as ZBED3 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZBED3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger BED domain-containing protein 3
NCBI Official Synonym Full Names
zinc finger, BED-type containing 3
NCBI Official Symbol
ZBED3
UniProt Protein Name
Zinc finger BED domain-containing protein 3
UniProt Synonym Protein Names
Axin-interacting protein
UniProt Gene Name
ZBED3
UniProt Entry Name
ZBED3_HUMAN
NCBI Protein Information
zinc finger BED domain-containing protein 3; 2610005H11Rik; axin-interacting protein; zinc finger, BED domain containing 3

UniProt Comments for ZBED3

ZBED3: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression. Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: membrane; cytosol

Molecular Function: DNA binding; metal ion binding

Biological Process: Wnt receptor signaling pathway; negative regulation of protein amino acid phosphorylation; protein stabilization; positive regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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