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SH3RF2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151521

SH3RF2 Antibody: Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SH3RF2, Polyclonal Antibody
Full Product Name
SH3RF2 Antibody
Product Gene Name
Product Synonym Names
SH3RF2; HEPP1; POSHER; RNF158; PPP1R39; Putative E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; SH3 domain containing ring finger 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
SH3RF2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
SH3RF2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
SH3RF2 peptide (MBS153021) is used for blocking the activity of SH3RF2 antibody (MBS151521)
Molecular Weight
19,895 Da
OMIM
613377
3D Structure
ModBase 3D Structure for Q8TEC5
Conjugate
Unconjugated
Immunogen
SH3RF2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SH3RF2.
Buffer
SH3RF2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SH3RF2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SH3RF2 antibody
SH3RF2 antibody can be used for detection of SH3RF2 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SH3RF2 antibody

Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-SH3RF2 Polyclonal Antibody – Cat# MBS151521

Immunohistochemistry (IHC) of anti-SH3RF2 antibody

Immunohistochemistry of SH3RF2 in human brain tissue with SH3RF2 antibody at 10 μg/mL.
Rabbit Anti-SH3RF2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151521

Immunofluorescence (IF) of anti-SH3RF2 antibody

Immunofluorescence of SH3RF2 in human brain tissue with SH3RF2 antibody at 20 μg/mL.
Rabbit Anti-SH3RF2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151521

Other Notes

Small volumes of anti-SH3RF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SH3RF2 purchase

MBS151521 is an antibody targeting SH3RF2. Also known as SH3RF2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SH3RF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
putative E3 ubiquitin-protein ligase SH3RF2
NCBI Official Synonym Full Names
SH3 domain containing ring finger 2
NCBI Official Symbol
SH3RF2
NCBI Official Synonym Symbols
HEPP1; POSHER; RNF158; PPP1R39
UniProt Protein Name
Putative E3 ubiquitin-protein ligase SH3RF2
UniProt Synonym Protein Names
Heart protein phosphatase 1-binding protein; HEPP1; Protein phosphatase 1 regulatory subunit 39; RING finger protein 158; SH3 domain-containing RING finger protein 2
UniProt Gene Name
SH3RF2
UniProt Synonym Gene Names
PPP1R39; RNF158; HEPP1
UniProt Entry Name
SH3R2_HUMAN
NCBI Protein Information
putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; POSH-eliminating RING protein; SH3 domain-containing RING finger protein 2; heart protein phosphatase 1-binding protein; protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39

UniProt Comments for SH3RF2

SH3RF2: Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function. Belongs to the SH3RF family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligase; EC 6.3.2.-; Ubiquitin ligase; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: nucleoplasm

Molecular Function: protein binding; zinc ion binding; protein phosphatase inhibitor activity; protein phosphatase 1 binding; phosphatase binding; ligase activity

Biological Process: protein ubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SH3RF2 antibody

 Reference Product  PubMed Publications
 SH3RF1 antibody  >1 publications with SH3RF2 and SH3RF1

Diseases associated with anti-SH3RF2 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with SH3RF2 and Necrosis

Organs/Tissues associated with anti-SH3RF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with SH3RF2 and Brain
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