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SLITRK5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151545

Slitrk5 Antibody: SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Slitrk5, Polyclonal Antibody
Full Product Name
Slitrk5 Antibody
Product Gene Name
Product Synonym Names
Slitrk5; LRRC11; bA364G4.2; KIAA0918; LRRC11; SLIT and NTRK-like protein 5; Leucine-rich repeat-containing protein 11; SLIT and NTRK-like family, member 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Slitrk5 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Preparation and Storage
Slitrk5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
Slitrk5 peptide (MBS153109) is used for blocking the activity of Slitrk5 antibody (MBS151545)
Molecular Weight
79,766 Da
OMIM
609680
3D Structure
ModBase 3D Structure for O94991
Conjugate
Unconjugated
Immunogen
Slitrk5 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Slitrk5.
Buffer
Slitrk5 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-SLITRK5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SLITRK5 antibody
Slitrk5 antibody can be used for detection of Slitrk5 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-SLITRK5 antibody

Western blot analysis of Slitrk5 in 3T3 cell lysate with Slitrk5 antibody at 1 μg/mL in the (A) absence or (B) presence of blocking peptide.
Rabbit Anti-SLITRK5 Polyclonal Antibody – Cat# MBS151545

Immunohistochemistry (IHC) of anti-SLITRK5 antibody

Immunohistochemistry of Slitrk5 in human brain tissue with Slitrk5 antibody at 2.5 μg/mL.
Rabbit Anti-SLITRK5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151545

Immunofluorescence (IF) of anti-SLITRK5 antibody

Immunofluorescence of slitrk5 in human brain tissue with slitrk5 antibody at 20 μg/mL.
Rabbit Anti-SLITRK5 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151545

Other Notes

Small volumes of anti-SLITRK5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLITRK5 purchase

MBS151545 is an antibody targeting SLITRK5. Also known as Slitrk5 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLITRK5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SLIT and NTRK-like protein 5
NCBI Official Synonym Full Names
SLIT and NTRK-like family, member 5
NCBI Official Symbol
SLITRK5
NCBI Official Synonym Symbols
LRRC11; bA364G4.2
UniProt Protein Name
SLIT and NTRK-like protein 5
UniProt Synonym Protein Names
Leucine-rich repeat-containing protein 11
UniProt Gene Name
SLITRK5
UniProt Synonym Gene Names
KIAA0918; LRRC11
UniProt Entry Name
SLIK5_HUMAN
NCBI Protein Information
SLIT and NTRK-like protein 5; slit and trk like gene 5; leucine rich repeat containing 11; leucine-rich repeat-containing protein 11

NCBI Summary for SLITRK5

Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SLITRK5

SLITRK5: Suppresses neurite outgrowth. Belongs to the SLITRK family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q31.2

Cellular Component: integral to membrane; receptor complex

Biological Process: grooming behavior; skin development; response to xenobiotic stimulus; synaptic transmission; striatum development; axonogenesis; adult behavior; dendrite morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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