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ZSCAN4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151547

ZSCAN4 Antibody: Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZSCAN4, Polyclonal Antibody
Full Product Name
ZSCAN4 Antibody
Product Gene Name
Product Synonym Names
ZNF494; ZNF494; Zinc finger and SCAN domain-containing protein 4; Zinc finger protein 494; zinc finger and SCAN domain containing 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
ZSCAN4 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZSCAN4 peptide (MBS152916) is used for blocking the activity of ZSCAN4 antibody (MBS151547)
Molecular Weight
48,957 Da
OMIM
613419
3D Structure
ModBase 3D Structure for Q8NAM6
Conjugate
Unconjugated
Immunogen
ZSCAN4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZSCAN4.
Buffer
ZSCAN4 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ZSCAN4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ZSCAN4 antibody
ZSCAN4 antibody can be used for detection of ZSCAN4 by Western blot. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ZSCAN4 antibody

Western blot analysis of ZSCAN4 in mouse lung tissue lysate with ZSCAN4 antibody in (A) the absence and (B) presence of blocking peptide.
Rabbit Anti-ZSCAN4 Polyclonal Antibody – Cat# MBS151547

Immunohistochemistry (IHC) of anti-ZSCAN4 antibody

Immunohistochemistry of ZSCAN4 in rat lung tissue with ZSCAN4 antibody at 5 μg/mL.
Rabbit Anti-ZSCAN4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151547

Immunofluorescence (IF) of anti-ZSCAN4 antibody

Immunofluorescence of ZSCAN4 in Rat Lung tissue with ZSCAN4 antibody at 20 μg/mL.
Rabbit Anti-ZSCAN4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151547

Other Notes

Small volumes of anti-ZSCAN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZSCAN4 purchase

MBS151547 is an antibody targeting ZSCAN4. Also known as ZSCAN4 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZSCAN4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger and SCAN domain-containing protein 4
NCBI Official Synonym Full Names
zinc finger and SCAN domain containing 4
NCBI Official Symbol
ZSCAN4
NCBI Official Synonym Symbols
ZNF494
UniProt Protein Name
Zinc finger and SCAN domain-containing protein 4
UniProt Synonym Protein Names
Zinc finger protein 494
UniProt Gene Name
ZSCAN4
UniProt Synonym Gene Names
ZNF494
UniProt Entry Name
ZSCA4_HUMAN
NCBI Protein Information
zinc finger and SCAN domain-containing protein 4; zinc finger protein 494

NCBI Summary for ZSCAN4

The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]
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UniProt Comments for ZSCAN4

ZSCAN4: Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.

Protein type: C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: nuclear chromosome, telomeric region

Molecular Function: DNA binding; metal ion binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZSCAN4 antibody

Organs/Tissues associated with anti-ZSCAN4 antibody

 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >1 publications with ZSCAN4 and Placenta
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