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ZBTB4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151571

ZBTB4 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. Similar to Kaiso, a zinc-finger containing protein that can bind methylated CpGs, ZBTB4 can also bind methylated DNA… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZBTB4, Polyclonal Antibody
Full Product Name
ZBTB4 Antibody
Product Gene Name
anti-ZBTB4 antibody
Product Synonym Names
ZBTB4; ZNF903; KAISO-L1; KIAA1538; Zinc finger and BTB domain-containing protein 4; KAISO-like zinc finger protein 1; zinc finger and BTB domain containing 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
ZBTB4 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least four isoforms of ZBTB4 are known to exist; this antibody will only recognize the longest isoform. This antibody is predicted to not cross-react with other ZBTB protein family members.
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
ZBTB4 peptide (MBS152176) is used for blocking the activity of ZBTB4 antibody (MBS151571)
Molecular Weight
105,114 Da
OMIM
612308
3D Structure
ModBase 3D Structure for Q9P1Z0
Conjugate
Unconjugated
Immunogen
ZBTB4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZBTB4.
Buffer
ZBTB4 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-ZBTB4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-ZBTB4 antibody
ZBTB4 antibody can be used for detection of ZBTB4 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ZBTB4 antibody

Western blot analysis of ZBTB4 in SK-N-SH cell lysate with ZBTB4 antibody at 1 μg/mL.
Rabbit Anti-ZBTB4 Polyclonal Antibody – Cat# MBS151571

Immunohistochemistry (IHC) of anti-ZBTB4 antibody

Immunohistochemistry of ZBTB4 in human brain tissue with ZBTB4 antibody at 2.5 μg/mL.
Rabbit Anti-ZBTB4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151571

Immunofluorescence (IF) of anti-ZBTB4 antibody

Immunofluorescence of ZBTB4 in human brain tissue with ZBTB4 antibody at 20 μg/mL.
Rabbit Anti-ZBTB4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151571

Other Notes

Small volumes of anti-ZBTB4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZBTB4 purchase

MBS151571 is an antibody targeting ZBTB4. Also known as ZBTB4 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZBTB4. It may not necessarily be applicable to this product.

NCBI GI #
192807286
NCBI GeneID
57659
NCBI Accession #
EAW90185
UniProt Primary Accession #
Q9P1Z0
UniProt Secondary Accession #
Q7Z697; Q86XJ4; Q8N4V8; B3KVL6
UniProt Related Accession #
Q9P1Z0
GenBank Nucleotide #
NM_001128833.1
NCBI Official Full Name
zinc finger and BTB domain-containing protein 4
NCBI Official Synonym Full Names
zinc finger and BTB domain containing 4
NCBI Official Symbol
ZBTB4
NCBI Official Synonym Symbols
ZNF903; KAISO-L1
UniProt Protein Name
Zinc finger and BTB domain-containing protein 4
UniProt Synonym Protein Names
KAISO-like zinc finger protein 1; KAISO-L1
Protein Family
Zinc finger and BTB domain-containing protein
UniProt Gene Name
ZBTB4
UniProt Synonym Gene Names
KIAA1538; KAISO-L1
UniProt Entry Name
ZBTB4_HUMAN
NCBI Protein Information
zinc finger and BTB domain-containing protein 4; KAISO-like zinc finger protein 1

UniProt Comments for ZBTB4

ZBTB4: May be involved in transcriptional regulation.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: nucleus

Molecular Function: protein binding; protein homodimerization activity; methyl-CpG binding; sequence-specific DNA binding; metal ion binding; protein kinase binding; methyl-CpNpG binding

Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to DNA damage stimulus
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Research Articles on ZBTB4

1. ZBTB4 functions as a novel tumor-suppressor gene with prognostic significance for breast cancer survival

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ZBTB4 antibody

 Reference Product  PubMed Publications
 CDKN1A antibody  >2 publications with ZBTB4 and CDKN1A
 SIN3B antibody  >1 publications with ZBTB4 and SIN3B
 SIN3A antibody  >1 publications with ZBTB4 and SIN3A

Diseases associated with anti-ZBTB4 antibody

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with ZBTB4 and Immune System Diseases
 Carcinoma Antibodies  >1 publications with ZBTB4 and Carcinoma
 Neoplasms, Experimental Antibodies  >1 publications with ZBTB4 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >1 publications with ZBTB4 and Breast Neoplasms
 Urinary Bladder Neoplasms Antibodies  >1 publications with ZBTB4 and Urinary Bladder Neoplasms

Organs/Tissues associated with anti-ZBTB4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with ZBTB4 and Blood
 Vascular Antibodies  >2 publications with ZBTB4 and Vascular
 Prostate Antibodies  >1 publications with ZBTB4 and Prostate
 Uncharacterized Tissue Antibodies  >1 publications with ZBTB4 and Uncharacterized Tissue
 Lung Antibodies  >1 publications with ZBTB4 and Lung
 Brain Antibodies  >1 publications with ZBTB4 and Brain
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