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RCAN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS151578

RCAN2 Antibody: Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously… More details

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Product Documentation
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RCAN2, Polyclonal Antibody
Full Product Name
RCAN2 Antibody
Product Gene Name
anti-Rcan2 antibody
Product Synonym Names
RCAN2; Csp2; MCIP2; ZAKI-4; Dscr1l1; Zaki4; Calcipressin-2; Calcineurin inhibitory protein ZAKI-4; regulator of calcineurin 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
RCAN2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
RCAN2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
RCAN2 peptide (MBS152156) is used for blocking the activity of RCAN2 antibody (MBS151578)
Molecular Weight
22,025 Da
3D Structure
ModBase 3D Structure for Q9JHG2
Conjugate
Unconjugated
Immunogen
RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2.
Buffer
RCAN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-Rcan2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-Rcan2 antibody
RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-Rcan2 antibody

Western blot analysis of RCAN2 in 3T3 cell lysate with RCAN2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-RCAN2 Polyclonal Antibody – Cat# MBS151578

Immunohistochemistry (IHC) of anti-Rcan2 antibody

Immunohistochemistry of RCAN2 in mouse brain tissue with RCAN2 antibody at 2.5 μg/mL.
Rabbit Anti-RCAN2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS151578

Immunofluorescence (IF) of anti-Rcan2 antibody

Immunofluorescence of RCAN2 in mouse brain tissue with RCAN2 antibody at 20 μg/mL.
Rabbit Anti-RCAN2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS151578

Other Notes

Small volumes of anti-Rcan2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rcan2 purchase

MBS151578 is an antibody targeting Rcan2. Also known as RCAN2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Rcan2. It may not necessarily be applicable to this product.

NCBI GI #
38328420
NCBI GeneID
53901
NCBI Accession #
AAH62141
UniProt Primary Accession #
Q9JHG2
UniProt Secondary Accession #
Q8VIP5
UniProt Related Accession #
Q9JHG2
NCBI Official Full Name
Rcan2 protein
NCBI Official Synonym Full Names
regulator of calcineurin 2
NCBI Official Symbol
Rcan2
NCBI Official Synonym Symbols
Csp2; MCIP2; ZAKI-4; Dscr1l1
UniProt Protein Name
Calcipressin-2
UniProt Synonym Protein Names
Calcineurin inhibitory protein ZAKI-4; Down syndrome candidate region 1-like protein 1; Myocyte-enriched calcineurin-interacting protein 2; MCIP2; Regulator of calcineurin 2
Protein Family
Calcipressin
UniProt Gene Name
Rcan2
UniProt Synonym Gene Names
Dscr1l1; Zaki4; MCIP2
UniProt Entry Name
RCAN2_MOUSE
NCBI Protein Information
calcipressin-2; calcineurin inhibitory protein ZAKI-4; Down syndrome critical region gene 1-like 1; down syndrome candidate region 1-like protein 1; myocyte-enriched calcineurin interactin protein 2; myocyte-enriched calcineurin-interacting protein 2

UniProt Comments for Rcan2

RCAN2: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: intracellular

Molecular Function: nucleotide binding

Biological Process: calcineurin-NFAT signaling pathway; short-term memory; calcium-mediated signaling; response to stress; response to oxidative stress; locomotion during locomotory behavior
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Research Articles on Rcan2

1. Rcan2 regulates osteoblast function and its expression in bone is regulated by thyroid status in vivo

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Rcan2 antibody

 Products by Pathway  Pathway Diagram
 Thyroid Hormone Signaling Pathway antibodies  Thyroid Hormone Signaling Pathway Diagram

Diseases associated with anti-Rcan2 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with Rcan2 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >4 publications with Rcan2 and Congenital Abnormalities
 Hypertrophy Antibodies  >3 publications with Rcan2 and Hypertrophy
 Atrophy Antibodies  >2 publications with Rcan2 and Atrophy
 Inflammation Antibodies  >2 publications with Rcan2 and Inflammation
 Brain Diseases Antibodies  >1 publications with Rcan2 and Brain Diseases
 Heart Diseases Antibodies  >1 publications with Rcan2 and Heart Diseases
 Weight Gain Antibodies  >1 publications with Rcan2 and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with Rcan2 and Disease Models, Animal
 Learning Disorders Antibodies  >1 publications with Rcan2 and Learning Disorders

Organs/Tissues associated with anti-Rcan2 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >20 publications with Rcan2 and Muscle
 Brain Antibodies  >7 publications with Rcan2 and Brain
 Heart Antibodies  >5 publications with Rcan2 and Heart
 Kidney Antibodies  >3 publications with Rcan2 and Kidney
 Spinal Cord Antibodies  >3 publications with Rcan2 and Spinal Cord
 Liver Antibodies  >2 publications with Rcan2 and Liver
 Thymus Antibodies  >1 publications with Rcan2 and Thymus
 Pancreas Antibodies  >1 publications with Rcan2 and Pancreas
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