Mouse Anti-GAG Monoclonal Antibody – Cat# MBS153317

Western blot analysis of 20 ng of recombinant HIV-1 p24 protein with PM-6335-HRP at 0.2 μg/mL.

HIV-1 P24 (GAG) Antibody – Mouse Monoclonal

Name: GAG Antibody; Monoclonal; Mouse; Virus-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS153317
Price: 530 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153317

HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1). The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix… More details

$530 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HIV-1 p24 (GAG), Monoclonal Antibody

Full Product Name

HIV-1 p24 Antibody [8G9]

Product Gene Name

anti-GAG antibody

Product Synonym Names

HIV-1 p24 Antibody [8G9]; gag Pr55(Gag)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

8G9

Host

Mouse

Species Reactivity

Virus

Form/Format

Liquid

Purity/Purification

HIV-1 p24 antibody is supplied as protein A purified IgG1.

Concentration

1 mg/mL (lot specific)

Specificity

By Western blot, anti-HIV-1 p24 antibody detects a ~24 kDa, a ~41 kDa, and a ~55 kDa protein, corresponding to HIV-1 p24 and to its precursors p41 and p55, respectively, in HIV-1 samples.

Preparation and Storage

HIV-1 p24 Monoclonal Antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Molecular Weight

Predicted: 24; 41; 55 kDa

3D Structure

ModBase 3D Structure for P04591

Conjugate

HRP

Immunogen

Mouse monoclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein.

Buffer

HIV-1 p24 antibody is supplied in PBS containing 0.02% thimerosal.

Applications Tested/Suitable for anti-GAG antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-GAG antibody

PM-6335-HRP can be used for detection of p24 by Western blot or ELISA at 0.2 - 0.5mug/mL.

Other Notes

Small volumes of anti-GAG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAG purchase

MBS153317 is an antibody targeting GAG. Also known as HIV-1 p24 Antibody [8G9]. Reactive in Virus. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GAG. It may not necessarily be applicable to this product.

NCBI GI #

327745

NCBI GeneID

155030

NCBI Accession #

AAB50258

UniProt Primary Accession #

P04591

UniProt Related Accession #

Q77YG1

NCBI Official Full Name

gag polyprotein

NCBI Official Symbol

gag

UniProt Protein Name

Gag polyprotein

UniProt Synonym Protein Names

Pr55GagCleaved into the following 6 chains:Matrix protein p17; MA; Capsid protein p24; CA; Spacer peptide p2; Nucleocapsid protein p7; NC; Spacer peptide p1; p6-gag

Protein Family

Core protein

UniProt Gene Name

gag

UniProt Synonym Gene Names

MA; CA; NC

UniProt Entry Name

GAG_HV1H2

NCBI Protein Information

Pr55(Gag); matrix; capsid; nucleocapsid; p2; p6; p1

UniProt Comments for GAG

Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).

Research Articles on GAG

1. These data show that naturally occurring sequence variations within HLA-C03:04-restricted HIV-1 p24 Gag epitopes can have a significant impact on the binding of inhibitory KIR2DL2 receptors and primary natural killer cell function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GAG antibody

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2-LTR Circle Formation Pathway antibodies	2-LTR Circle Formation Pathway Diagram
APOBEC3G Mediated Resistance To HIV-1 Infection Pathway antibodies	APOBEC3G Mediated Resistance To HIV-1 Infection Pathway Diagram
Assembly Of The HIV Virion Pathway antibodies	Assembly Of The HIV Virion Pathway Diagram
Autointegration Results In Viral DNA Circles Pathway antibodies	Autointegration Results In Viral DNA Circles Pathway Diagram
Binding And Entry Of HIV Virion Pathway antibodies	Binding And Entry Of HIV Virion Pathway Diagram
Budding And Maturation Of HIV Virion Pathway antibodies	Budding And Maturation Of HIV Virion Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Early Phase Of HIV Life Cycle Pathway antibodies	Early Phase Of HIV Life Cycle Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram