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GLIPR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153334

The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased… More details

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Product Overview

Online Datasheet in PDF
Product Name
GLIPR1, Polyclonal Antibody
Full Product Name
GLIPR1 Antibody
Product Gene Name
anti-GLIPR1 antibody
Product Synonym Names
GLIPR1; GLIPR; RTVP1; CRISP7; GLIPR; Glioma pathogenesis-related protein 1; Protein RTVP-1; GliPR 1; GLI pathogenesis-related 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
GLIPR1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
Preparation and Storage
GLIPR1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
GLIPR1 peptide (MBS153984) is used for blocking the activity of GLIPR1 antibody (MBS153334)
Molecular Weight
Predicted: 29 kDa

Observed: 24 kDa
OMIM
602692
3D Structure
ModBase 3D Structure for P48060
Conjugate
Unconjugated
Immunogen
GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1.
Buffer
GLIPR1 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-GLIPR1 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-GLIPR1 antibody
GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 mug/ml. For Immunoflorescence start at 5 mug/mL.

Western Blot (WB) of anti-GLIPR1 antibody

Western blot analysis of GLIPR1 in human small intestine tissue lysate with GLIPR1 antibody at 1 μg/ml.
Rabbit Anti-GLIPR1 Polyclonal Antibody – Cat# MBS153334

Immunofluorescence (IF) of anti-GLIPR1 antibody

Immunoflorescence of GLIPR1 in human small intestine tissue with GLIPR1 antibody at 5 μg/mL.
Rabbit Anti-GLIPR1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153334

Other Notes

Small volumes of anti-GLIPR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLIPR1 purchase

MBS153334 is an antibody targeting GLIPR1. Also known as GLIPR1 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLIPR1. It may not necessarily be applicable to this product.

NCBI GI #
110825980
NCBI GeneID
11010
NCBI Accession #
NP_006842
UniProt Primary Accession #
P48060
UniProt Secondary Accession #
Q15409; Q969K2; A7YET6; F8VUC2
UniProt Related Accession #
P48060
GenBank Nucleotide #
NM_006851.2
NCBI Official Full Name
glioma pathogenesis-related protein 1
NCBI Official Synonym Full Names
GLI pathogenesis-related 1
NCBI Official Symbol
GLIPR1
NCBI Official Synonym Symbols
GLIPR; RTVP1; CRISP7
UniProt Protein Name
Glioma pathogenesis-related protein 1
UniProt Synonym Protein Names
Protein RTVP-1
Protein Family
Glioma pathogenesis-related protein
UniProt Gene Name
GLIPR1
UniProt Synonym Gene Names
GLIPR; RTVP1; GliPR 1
UniProt Entry Name
GLIP1_HUMAN
NCBI Protein Information
glioma pathogenesis-related protein 1; gliPR 1; protein RTVP-1; GLI pathogenesis-related 1 (glioma); testes-specific vespid and pathogenesis protein 1; related to testis-specific, vespid, and pathogenesis proteins 1

NCBI Summary for GLIPR1

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
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UniProt Comments for GLIPR1

GLIPR1: a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q21.2

Cellular Component: membrane; plasma membrane; integral to membrane; extracellular region

Biological Process: cellular lipid metabolic process
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Research Articles on GLIPR1

1. Data indicate that combining adenoviral vector-mediated GLIPR1 gene therap (AdGLIPR1) with radiotherapy may achieve additive or synergistic tumor control in selected prostate and bladder tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLIPR1 antibody

 Products by Pathway  Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram

Diseases associated with anti-GLIPR1 antibody

 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >3 publications with GLIPR1 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >3 publications with GLIPR1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >3 publications with GLIPR1 and Disease Models, Animal
 Lung Neoplasms Antibodies  >3 publications with GLIPR1 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with GLIPR1 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >2 publications with GLIPR1 and Neoplasms, Experimental
 Wilms Tumor Antibodies  >2 publications with GLIPR1 and Wilms Tumor
 Urinary Bladder Neoplasms Antibodies  >1 publications with GLIPR1 and Urinary Bladder Neoplasms
 Kidney Diseases Antibodies  >1 publications with GLIPR1 and Kidney Diseases
 Fever Antibodies  >1 publications with GLIPR1 and Fever

Organs/Tissues associated with anti-GLIPR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >21 publications with GLIPR1 and Prostate
 Brain Antibodies  >9 publications with GLIPR1 and Brain
 Blood Antibodies  >6 publications with GLIPR1 and Blood
 Bone Antibodies  >6 publications with GLIPR1 and Bone
 Bone Marrow Antibodies  >5 publications with GLIPR1 and Bone Marrow
 Lung Antibodies  >4 publications with GLIPR1 and Lung
 Testis Antibodies  >4 publications with GLIPR1 and Testis
 Bladder Antibodies  >2 publications with GLIPR1 and Bladder
 Kidney Antibodies  >2 publications with GLIPR1 and Kidney
 Skin Antibodies  >1 publications with GLIPR1 and Skin
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