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WAPAL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153367

WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1). It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and… More details

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Product Overview

Online Datasheet in PDF
Product Name
WAPL (WAPAL), Polyclonal Antibody
Full Product Name
WAPL Antibody
Product Gene Name
Product Synonym Names
WAPL; FOE; WAPL; KIAA0261; FOE; Wings apart-like protein homolog; Friend of EBNA2 protein; wings apart-like homolog (Drosophila)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
WAPL antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
WAPL peptide (MBS154162) is used for blocking the activity of WAPL antibody (MBS153367)
Molecular Weight
Predicted: 131 kDa

Observed: 140 kDa
OMIM
610754
3D Structure
ModBase 3D Structure for Q7Z5K2
Conjugate
Unconjugated
Immunogen
WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL.
Buffer
WAPL antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-WAPAL antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-WAPAL antibody
WAPL antibody can be used for detection of WAPL by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry at 5 mug/mL. For Immunoflorescence start at 20 mug/mL.

Western Blot (WB) of anti-WAPAL antibody

Western blot analysis of WAPL in A20 cell lysate with WAPL antibody at (A) 1 and (B) 2 μg/ml.
Rabbit Anti-WAPAL Polyclonal Antibody – Cat# MBS153367

Immunohistochemistry (IHC) of anti-WAPAL antibody

Immunohistochemistry of WAPL in rat heart tissue with WAPL antibody at 5 μg/mL.
Rabbit Anti-WAPAL Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153367

Immunofluorescence (IF) of anti-WAPAL antibody

Immunofluorescence of WAPL in rat heart tissue with WAPL antibody at 20 μg/mL.
Rabbit Anti-WAPAL Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153367

Other Notes

Small volumes of anti-WAPAL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WAPAL purchase

MBS153367 is an antibody targeting WAPAL. Also known as WAPL Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WAPAL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
wings apart-like protein homolog
NCBI Official Synonym Full Names
wings apart-like homolog (Drosophila)
NCBI Official Symbol
WAPAL
NCBI Official Synonym Symbols
FOE; WAPL; KIAA0261
UniProt Protein Name
Wings apart-like protein homolog
UniProt Synonym Protein Names
Friend of EBNA2 protein
UniProt Gene Name
WAPAL
UniProt Synonym Gene Names
FOE; KIAA0261; WAPL
UniProt Entry Name
WAPL_HUMAN
NCBI Protein Information
wings apart-like protein homolog; friend of EBNA2 protein; friend of EBNA2 (Epstein-Barr virus nuclear protein 2)

UniProt Comments for WAPAL

WAPL: a chromatin-associated protein partner of Epstein-Barr nuclear protein 2. Associated with cervical carcinogenesis and tumor progression.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 10q23.2

Cellular Component: cohesin complex; microtubule cytoskeleton; nucleoplasm; intracellular membrane-bound organelle; cytoplasm; synaptonemal complex; chromosome; cytosol; nucleus; chromatin; chromosome, pericentric region

Molecular Function: protein binding

Biological Process: mitosis; positive regulation of fibroblast proliferation; viral reproduction; cell division; negative regulation of DNA replication; response to toxin; negative regulation of sister chromatid cohesion; mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-WAPAL antibody

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