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LRRC26 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153399

The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1). LRRC26 was later found to negatively… More details

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Product Overview

Online Datasheet in PDF
Product Name
LRRC26, Polyclonal Antibody
Full Product Name
LRRC26 Antibody
Product Gene Name
Product Synonym Names
LRRC26; CAPC; bA350O14.10; CAPC; Leucine-rich repeat-containing protein 26; BK channel auxiliary gamma subunit LRRC26; leucine rich repeat containing 26
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
LRRC26 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
LRRC26 antibody is human specific.
Preparation and Storage
LRRC26 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
LRRC26 peptide (MBS153893) is used for blocking the activity of LRRC26 antibody (MBS153399)
Molecular Weight
Predicted: 37 kDa

Observed: 48 kDa
OMIM
613505
3D Structure
ModBase 3D Structure for Q2I0M4
Conjugate
Unconjugated
Immunogen
LRRC26 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRRC26.
The immunogen is located within the last 50 amino acids of LRRC26.
Buffer
LRRC26 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-LRRC26 antibody
ELISA, IHC-P, WB
Application Notes for anti-LRRC26 antibody
LRRC26 antibody can be used for detection of LRRC26 by Western blot at 0.5 - 1 ug/ml. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL.

Optimal dilutions for each application to be determined by the researcher.
Positive Control:
1) Cat. No. MBS151661 - Human Prostate Tissue Lysate
2) Cat. No. MBS151729 - Jurkat Cell Lysate

Western Blot (WB) of anti-LRRC26 antibody

Western blot analysis of LRRC26 in human prostate tissue lysate with LRRC26 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-LRRC26 Polyclonal Antibody – Cat# MBS153399

Immunohistochemistry (IHC) of anti-LRRC26 antibody

Immunohistochemistry of LRRC26 in human prostate tissue with LRRC26 antibody at 2.5 μg/mL.
Rabbit Anti-LRRC26 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153399

Immunohistochemistry (IHC) of anti-LRRC26 antibody

Immunohistochemistry of LRRC26 in human prostate tissue with LRRC26 antibody at 2.5 μg/ml.
Rabbit Anti-LRRC26 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153399

Western Blot (WB) of anti-LRRC26 antibody

Western blot analysis of LRRC26 in Jurkat cell lysate with LRRC26 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-LRRC26 Polyclonal Antibody, Western Blot (WB) – Cat# MBS153399

Immunofluorescence (IF) of anti-LRRC26 antibody

Immunofluorescence of LRRC26 in human prostate tissue with LRRC26 Antibody at 20 μg/mL.
Rabbit Anti-LRRC26 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153399

Other Notes

Small volumes of anti-LRRC26 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRRC26 purchase

MBS153399 is an antibody targeting LRRC26. Also known as LRRC26 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRC26. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
leucine-rich repeat-containing protein 26
NCBI Official Synonym Full Names
leucine rich repeat containing 26
NCBI Official Symbol
LRRC26
NCBI Official Synonym Symbols
CAPC; bA350O14.10
UniProt Protein Name
Leucine-rich repeat-containing protein 26
UniProt Synonym Protein Names
BK channel auxiliary gamma subunit LRRC26; Cytokeratin-associated protein in cancer
UniProt Gene Name
LRRC26
UniProt Synonym Gene Names
CAPC
UniProt Entry Name
LRC26_HUMAN
NCBI Protein Information
leucine-rich repeat-containing protein 26; cytokeratin associated protein; cytokeratin-associated protein in cancer; BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26

UniProt Comments for LRRC26

LRRC26: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low- voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: voltage-gated potassium channel complex; cytoskeleton; cytoplasm

Molecular Function: protein binding; potassium channel regulator activity

Biological Process: ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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