• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AIMP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153415

AIMP2 was initially identified as a part of an aminoacyl-tRNA synthesase complex (1). It was later discovered to be a cofactor and substrate of Parkin, a Ring-type E3 ubiquitin ligase that is important for the survival of dopamine neurons in Parkinson's… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AIMP2, Polyclonal Antibody
Full Product Name
AIMP2 Antibody
Product Gene Name
Product Synonym Names
AIMP2; P38; JTV1; JTV-1; PRO0992; Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Multisynthase complex auxiliary component p38; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
AIMP2 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
AIMP2 antibody is human specific. AIMP2 antibody is predicted to not cross-react with AIMP1.
Preparation and Storage
AIMP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
AIMP2 peptide (MBS153779) is used for blocking the activity of AIMP2 antibody (MBS153415)
Molecular Weight
Predicted: 35 kDa

Observed: 36 kDa
OMIM
600859
3D Structure
ModBase 3D Structure for Q13155
Conjugate
Unconjugated
Immunogen
AIMP2 antibody was raised against a 16 amino acid peptide near the center of human AIMP2.
Buffer
AIMP2 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-AIMP2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-AIMP2 antibody
AIMP2 antibody can be used for detection of AIMP2 by Western blot at 1 - 2 mug/ml.

Western Blot (WB) of anti-AIMP2 antibody

Western blot analysis of AIMP2 in HeLa cell lysate with AIMP2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-AIMP2 Polyclonal Antibody – Cat# MBS153415

Immunohistochemistry (IHC) of anti-AIMP2 antibody

Immunohistochemistry of AIMP2 in rat small intestine tissue with AIMP2 antibody at 5 μg/mL.
Rabbit Anti-AIMP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153415

Immunofluorescence (IF) of anti-AIMP2 antibody

Immunofluorescence of AIMP2 in rat small intestine tissue with AIMP2 antibody at 20 μg/mL.
Rabbit Anti-AIMP2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153415

Other Notes

Small volumes of anti-AIMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AIMP2 purchase

MBS153415 is an antibody targeting AIMP2. Also known as AIMP2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AIMP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
aminoacyl tRNA synthase complex-interacting multifunctional protein 2
NCBI Official Synonym Full Names
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
NCBI Official Symbol
AIMP2
NCBI Official Synonym Symbols
P38; JTV1; JTV-1; PRO0992
UniProt Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
UniProt Synonym Protein Names
Multisynthase complex auxiliary component p38; Protein JTV-1
UniProt Gene Name
AIMP2
UniProt Synonym Gene Names
JTV1
UniProt Entry Name
AIMP2_HUMAN
NCBI Protein Information
aminoacyl tRNA synthase complex-interacting multifunctional protein 2; protein JTV-1; ARS-interacting multi-functional protein 2; multisynthase complex auxiliary component p38; multisynthetase complex auxiliary component p38

NCBI Summary for AIMP2

The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for AIMP2

JTV1: Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: membrane; nucleus; cytosol

Molecular Function: protein binding

Biological Process: negative regulation of cell proliferation; tRNA aminoacylation for protein translation; positive regulation of protein ubiquitination; apoptosis; gene expression
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000